Chemical study towards the structural diversity elucidation of the chemical constituents contained in hallucinogenic plants.
Chemical study towards the structural diversity elucidation of the chemical constituents contained in hallucinogenic plants.
批准号:
22590030
负责人:
SHIROTA Osamu
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
对致幻植物阿拉伯茶(Catha edulis)中所含的卡西酮及其推定的生物合成中间体麻黄碱进行了综合合成。并对不含麻黄碱的美洲麻黄进行了化学成分检索。在此基础上,对光亲和标记试剂和光解离受体钓鱼竿试剂的合成进行了研究。
英文摘要
Comprehensive syntheses of the analogs were proceeded, respectively about cathinone contained in a hallucinogenic plant Khat (Catha edulis), and its presumed biosynthetic intermediate ephedrine. Moreover, chemical constituents search of Ephedra americana in which ephedrine is not contained was performed. Furthermore, syntheses of the reagents for biosynthetic study were advanced about the photo-affinity labeling reagent and the photo-dissociation receptor fishing rod reagent that has fished the labeled biosynthetic enzyme, respectively.
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