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Histological analysis of T cell differentiation process based on hypermulticolor-hypersensitive fluorescence imaging method

Histological analysis of T cell differentiation process based on hypermulticolor-hypersensitive fluorescence imaging method
基于超多色-超灵敏荧光成像方法的T细胞分化过程的组织学分析
批准号:
22590194
负责人:
TSURUI Hiromichi
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
As the methods to evaluate chromophore-antibody conjugation state, gel-filtration chromatography, fluorescence-correlation spectroscopy, hyper-sensitive spectral imaging and high-magnification SEM were established or applied. Through those methods, two conjugation methods were established and applied to simultaneous imaging of T -bet, GATA-3, ROR-gt, FoxP3. IL-10 and IFN-a were also successfully imaged.
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会议论文
Phenotype conversion from RA to SLE in FcγRIIB-deficient B6 mice by Yaa mutation
Yaa 突变导致 FcγRIIB 缺陷 B6 小鼠从 RA 向 SLE 的表型转变
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [KAWANO Shinya, AMANO Hirofumi, LIN Qingshun, KANEKO Toshiyuki, NISHIKAWA Keiko, OKAZAKI Hideki, TSURUI Hiromichi, NISHIMURA Hiroyuki, SHIRAI Toshikazu, TAKASAKI Yoshinari, HIROSE Sachiko.]
通讯作者: HIROSE Sachiko.
Practical Estimation of TCR-pMHC binding free-energy based on the dielectric model and the Coarse-grained model in “Molecular Dynamics - Studies of Synthetic and Biological Macromolecules”
《分子动力学-合成与生物大分子的研究》中基于介电模型和粗粒度模型的TCR-pMHC结合自由能的实用估计
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [全〓坤, 前田誠司, 大谷(桑原)佐知, 田中宏一, 早川徹, 関真, Horiguchi K et al., Tsurui Hiromichi and Takahashi Takuya]
通讯作者: Tsurui Hiromichi and Takahashi Takuya
DOI: 10.1016/j.bbrc.2010.03.078
发表时间: 2010-04-09
期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
影响因子: 3.1
作者: [Ando, Seiichiro, Amano, Hirofumi, Takasaki, Yoshinari]
通讯作者: Takasaki, Yoshinari
Phagocytosis specific autofluorescence in marginal metallophilic macrophage and marginal zone macrophage
边缘嗜金属巨噬细胞和边缘区巨噬细胞的吞噬作用特异性自发荧光
DOI: --
发表时间: 2010
期刊: International Immunology
影响因子: 4.4
作者: [Tsurui H, Hirose S]
通讯作者: Hirose S
12
    Histological investigation of information pathway of antigen by hypermulticolor fluorescence imaging
    • 批准号:
      13670227
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.3万
    • 财政年份:
      2001
    • 负责人:
      TSURUI Hiromichi
    • 依托单位:
    The development of multi-color FISH for mRNA
    • 批准号:
      07807028
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.41万
    • 财政年份:
      1995
    • 负责人:
      TSURUI Hiromichi
    • 依托单位:
    海外基金