Medical Economic Evaluation of Noninvasive Blood Glucose Measurement with Respect to Sensitivity and Specificity.

无创血糖测量的敏感性和特异性的医学经济学评价。

• 批准号: 22590492
• 负责人: SAKAMAKI Hiroyuki
• 金额: $ 2.08万
• 依托单位: Meijo University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590492/
• 关键词: 医療経済学; 糖尿病; ガスクロマトグラフ－質量分析計; 支払意志額; 診断テスト分析; GC/MS; 医療経済; 仮想市場法

The study evaluated the usefulness of breath analysis as a noninvasive method of blood glucose measurement from both the scientific and economic viewpoint. A needle-type extraction device has been developed for efficient condensation of volatile organic substances contained in breath such as acetone, and the acetone concentration in breath was measured in healthy subjects and diabetic patients to evaluate the correlation with values obtained by blood testing. The economic value of this measurement method was evaluated by questionnaire survey on intention to pay in healthy subjects. Results suggest that it would be feasible to use this breath analysis for detection of diabetes.

该研究从科学和经济的角度评估了呼吸分析作为一种无创血糖测量方法的有效性。研制了一种针式提取装置，对呼气中挥发性有机物丙酮等进行高效冷凝，并对健康受试者和糖尿病患者的呼气中丙酮浓度进行测定，评价其与血液检测值的相关性。通过健康受试者支付意愿问卷调查，评价该测量方法的经济价值。结果表明，将这种呼吸分析方法用于糖尿病的检测是可行的。

项目成果

Novel Packed Capillary Columns in Gas Chromatography

气相色谱中的新型填充毛细管柱

• 发表时间: 2010
• 作者: I. Ueta;Y. Saito;K. Teraoka;T. Miura;K.Jinno;;M.Inoue;Y.Saito;Y. Saito;;近藤功行;Y. Saito;I.Ueta
• 通讯作者: I.Ueta

Sample Preparation Device for Human Breath Analysis in Capillary Gas Chromatography

毛细管气相色谱人体呼吸分析样品制备装置

• 发表时间: 2010
• 作者: I. Ueta;Y. Saito;K. Teraoka;T. Miura;K.Jinno;;M.Inoue;Y.Saito;Y. Saito;;近藤功行;Y. Saito
• 通讯作者: Y. Saito

Rapid Temperature Programming and Retention Prediction on Novel Packed-Capillary Columns in Gas Chromatography

气相色谱中新型填充毛细管柱的快速温度编程和保留预测

• 发表时间: 2011
• 作者: I. Ueta;Y. Saito;K. Teraoka;T. Miura;K.Jinno;;M.Inoue;Y.Saito
• 通讯作者: Y.Saito

ガスクロマトグラフィーのための針型試料前処理デバイス

气相色谱用针状样品制备装置

• 发表时间: 2011
• 期刊: BUNSEKI KAGAKU
• 影响因子: 0.2
• 作者: 植田郁生;齊戸美弘
• 通讯作者: 齊戸美弘

Rapid Temperature-Programmed Separation and Retention Prediction on Novel Packed-Capillary Column in Gas Chromatography

气相色谱中新型填充毛细管柱的快速程序升温分离和保留预测

• 发表时间: 2010
• 期刊: Analytical Sciences
• 影响因子: 1.6
• 作者: I. Ueta;Y. Saito;K. Teraoka;T. Miura;K.Jinno;;M.Inoue
• 通讯作者: M.Inoue