Molecular epidemiological study of viral gastroenteritis in Asia

亚洲病毒性胃肠炎的分子流行病学研究

• 批准号: 22590620
• 负责人: OKITSU Shoko
• 金额: $ 3万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22590620/
• 关键词: ウイルス; 小児; 胃腸炎; アジア; 分子疫学; 人獣共通感染症; 感染症; 動物; 下痢症; 環境

1. This study reported the detection and molecular characterization of norovirus and rotavirus in the stool samples collected from infants and children with acute gastroenteritis in Japan and Thailand. 2. This study evaluated newly developed immunochromatography kits (IC kit) for detection of norovirus, or rotavirus from clinical samples. Furthermore, this study evaluated an IC kit for simultaneous detection of 3 kinds of diarrheal viruses (rotaivirus, norovirus, and adenovirus). 3. This study also reported the detection of viruses in Picornaviridae family from stool samples collected from infants and children with acute gastroenteritis. 4. This study reported the genomic characterization of VP1 region of porcine kobuvirus in the porcine stool samples in Japan, and Thailand, and detection of the porcine kobuvirus in the serum samples from healthy piglets in Thailand. 5. This study reported the whole-genomic analysis of G3P[23], G9P[23] and G3P[13] rotaviruses isolated from pigle with diarrhea inThailand, 2006-2008.

1.本研究报告了从日本和泰国的急性胃肠炎婴儿和儿童粪便样本中检测到诺如病毒和轮状病毒的分子特征。2.本研究评估了新开发的免疫层析试剂盒（IC试剂盒）用于检测临床样本中的诺如病毒或轮状病毒。此外，本研究还对同时检测3种呼吸道病毒（轮状病毒、诺如病毒和腺病毒）的IC试剂盒进行了评价。3.本研究还报告了从急性胃肠炎的婴儿和儿童的粪便样品中检测到小核糖核酸病毒科病毒。4.本研究报道了日本和泰国猪粪便样品中猪科布病毒VP 1区的基因组特征，以及泰国健康仔猪血清样品中猪科布病毒的检测结果。5.本研究报告了2006-2008年从泰国腹泻仔猪中分离的G3 P [23]、G9 P [23]和G3 P [13]轮状病毒的全基因组分析。

项目成果

Immunochromatography test for rapid detection of diarrheal viruses.

用于快速检测腹泻病毒的免疫层析测试。

• 发表时间: 2010
• 作者: Pham NT;Okitsu S;Ushijima H.;Ohno S;Phan TG;Ohno S;Dieng H;Ohno S;Horie Y;Li Y;Ohno S;Phan TG;Okame M;Phan TG;Pham NT;Muller WEG;Trinh QD;Honma S;Phan TG;Sang XJ;Phan TG;Phan TG;Nguyen TA;Khamrin P;Dey SK;Khamrin P;Nguyen TA;Phan TG;Fujimoto T;Nguyen TA;Kihara Y;Khamrin P;Shiota T;Pham NTK;Pham NTK;牛島廣治;牛島廣治;牛島廣治;Dey SK;牛島廣治;牛島廣治;Dey SK;森田英嗣;Dey SK;Chan-it W;Chan-it Wisoot;Dey Shuvra;森田英嗣;Pham TKN;Pham Thi Kim Ngan;牛島廣治;Ushijima K;Khamrin P;Okitsu S.;牛島廣治
• 通讯作者: 牛島廣治

Emergence of norovirusGII/4 2006a and 2006b variants in hospitalized children with acute gastroenteritis in Thailand

泰国急性胃肠炎住院儿童中出现诺如病毒 GII/4 2006a 和 2006b 变种

• DOI: 10.7754/clin.lab.2012.120316
• 发表时间: 2013
• 期刊: Clin Lab
• 影响因子: 0.7
• 作者: Thongprachum A;Okitsu S;et al.
• 通讯作者: et al.

Novel picornaviruses in children and adults with diarrhea, Thailand

泰国儿童和成人腹泻中的新型小核糖核酸病毒

• 发表时间: 2012
• 作者: Miyauchi Y;Jesmin S;Shimojo N;Maeda S;Sakai S;Yokota T;Zaedi S;Mizutani T;Homma S;Aonuma K;Miyauchi T;Khamrin P
• 通讯作者: Khamrin P

ノロウイルス診断法の最近の知見

诺如病毒诊断方法的最新发现

• 发表时间: 2012
• 期刊: 小児科臨床
• 作者: Tsunematsu Y;Fukutomi M;Saruwatari T;Noguchi H;Hotta K;Tang Y;Watanabe K;牛島廣治
• 通讯作者: 牛島廣治

Human bocavirus infection in children with acute gastro-enteritis, Japan and Thailand

日本和泰国儿童急性胃肠炎的人类博卡病毒感染

• 发表时间: 2011
• 期刊: J Medical Virol
• 作者: 櫻庭均;他;Pham NTK
• 通讯作者: Pham NTK