课题基金 / 基金详情

Anti-estrogen regulates proton ion: A study looking for a new therapy of cystic fibrosis.

Anti-estrogen regulates proton ion: A study looking for a new therapy of cystic fibrosis.
抗雌激素调节质子离子:一项寻找囊性纤维化新疗法的研究。
批准号:
22590757
负责人:
YAMAMOTO Akiko
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

YAMAMOTO Akiko的其他基金

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中文摘要
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英文摘要
Pancreatic juice is an alkaline fluid that contains HCO_3^- rich fluid and digestive enzymes. Na^+-H^+ exchangers (NHE) are localized in both basolateral and apical membranes of various epithelia. In the present study, to investigate the role of apical NHE in HCO_3^- secretion from pancreatic duct cells, we identified the membrane localization of apical Na^+-H^+ exchangers, measured the activity of apical Na^+-H^+ exchange, and demonstrated the mechanisms to play a role of HCO_3^- secretion by pancreatic ductal epithelium.
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会议论文
【膵基礎研究の新しい潮流Bench to Bedをめざして】膵導管細胞機能とCFTRの役割
【走向实验室,胰腺基础研究新趋势】胰腺导管细胞功能及CFTR的作用
DOI: --
发表时间: 2010
期刊: 胆と膵
影响因子: --
作者: [石黒洋, 洪繁, 山本明子]
通讯作者: 山本明子
【再発性膵炎の病態と治療】 導管細胞機能からみた膵炎再発の原因とその対策
【复发性胰腺炎的病理与治疗】从导管细胞功能角度探讨复发性胰腺炎的原因及对策
DOI: --
发表时间: 2012
期刊: 胆と膵
影响因子: --
作者: [Hewett DG, Tanaka S, et al., 田中信治(分担執筆) 青笹克之・八尾隆史編, 田中信治, 田尻久雄監修田中信治,他 編, 田中信治編, 瀬尾由広, 瀬尾由広, 瀬尾由広, 洪 繁]
通讯作者: 洪 繁
Pancreatic duct dysfunction and pancreatitis
胰管功能障碍和胰腺炎
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [石黒洋, 洪繁, 山本明子, 山口 誠, Ishiguro H]
通讯作者: Ishiguro H
Fluid secretion from the pancreatic duct in PCK rats.
PCK 大鼠胰管的液体分泌。
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S, Wei M, Kondo T, Naruse S.]
通讯作者: Naruse S.
7
    The Regional Development and Women's Empowerment in Iran
    • 批准号:
      19K20539
    • 项目类别:
      Grant-in-Aid for Early-Career Scientists
    • 资助金额:
      $2.75万
    • 财政年份:
      2019
    • 负责人:
      YAMAMOTO Akiko
    • 依托单位:
    Investigation of the pathogenic mechanism of Sjogren's syndrome based on intracellular metabolism and establishment of novel therapeutic strategies
    Influence of imparfect self-knowledge on two-sided search with bargaining
    Study of Gender Norms by Social Contribution Activities in Iran :Examining Women's Role Concept
    • 批准号:
      16K13120
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2016
    • 负责人:
      YAMAMOTO Akiko
    • 依托单位: