Anti-estrogen regulates proton ion: A study looking for a new therapy of cystic fibrosis.
Anti-estrogen regulates proton ion: A study looking for a new therapy of cystic fibrosis.
批准号:
22590757
负责人:
YAMAMOTO Akiko
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Pancreatic juice is an alkaline fluid that contains HCO_3^- rich fluid and digestive enzymes. Na^+-H^+ exchangers (NHE) are localized in both basolateral and apical membranes of various epithelia. In the present study, to investigate the role of apical NHE in HCO_3^- secretion from pancreatic duct cells, we identified the membrane localization of apical Na^+-H^+ exchangers, measured the activity of apical Na^+-H^+ exchange, and demonstrated the mechanisms to play a role of HCO_3^- secretion by pancreatic ductal epithelium.
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【膵基礎研究の新しい潮流Bench to Bedをめざして】膵導管細胞機能とCFTRの役割
【走向实验室,胰腺基础研究新趋势】胰腺导管细胞功能及CFTR的作用
DOI:
--
发表时间:
2010
期刊:
胆と膵
影响因子:
--
作者:
[石黒洋, 洪繁, 山本明子]
通讯作者:
山本明子
【再発性膵炎の病態と治療】 導管細胞機能からみた膵炎再発の原因とその対策
【复发性胰腺炎的病理与治疗】从导管细胞功能角度探讨复发性胰腺炎的原因及对策
DOI:
--
发表时间:
2012
期刊:
胆と膵
影响因子:
--
作者:
[Hewett DG, Tanaka S, et al., 田中信治(分担執筆) 青笹克之・八尾隆史編, 田中信治, 田尻久雄監修田中信治,他 編, 田中信治編, 瀬尾由広, 瀬尾由広, 瀬尾由広, 洪 繁]
通讯作者:
洪 繁
Pancreatic duct dysfunction and pancreatitis
胰管功能障碍和胰腺炎
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[石黒洋, 洪繁, 山本明子, 山口 誠, Ishiguro H]
通讯作者:
Ishiguro H
Fluid secretion from the pancreatic duct in PCK rats.
PCK 大鼠胰管的液体分泌。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S, Wei M, Kondo T, Naruse S.]
通讯作者:
Naruse S.
NH4+パルス負荷による膵導管細胞内pH変化のコンピューター・シュミレーション
计算机模拟 NH4+ 脉冲负载引起的胰管细胞内 pH 变化
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[石黒洋, 洪繁, 山本明子, 山口 誠]
通讯作者:
山口 誠
共 7 条
The Regional Development and Women's Empowerment in Iran
-
批准号:19K20539
-
项目类别:Grant-in-Aid for Early-Career Scientists
-
资助金额:$2.75万
-
财政年份:2019
-
负责人:YAMAMOTO Akiko
-
依托单位:
Investigation of the pathogenic mechanism of Sjogren's syndrome based on intracellular metabolism and establishment of novel therapeutic strategies
-
批准号:17K19759
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.16万
-
财政年份:2017
-
负责人:YAMAMOTO Akiko
-
依托单位:
Influence of imparfect self-knowledge on two-sided search with bargaining
-
批准号:17K03639
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.83万
-
财政年份:2017
-
负责人:YAMAMOTO Akiko
-
依托单位:
Study of Gender Norms by Social Contribution Activities in Iran :Examining Women's Role Concept
-
批准号:16K13120
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2016
-
负责人:YAMAMOTO Akiko
-
依托单位:
Development of the evaluation method for biosolubility of nanoparticles/fibers under pulmonary alveoli environment
-
批准号:16K12637
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.33万
-
财政年份:2016
-
负责人:YAMAMOTO Akiko
-
依托单位:
The Work of Women in Contemporary Iran
-
批准号:26883001
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.75万
-
财政年份:2014
-
负责人:YAMAMOTO Akiko
-
依托单位:
Understanding and control of biodegradability of bioabsorbable Mg alloys
-
批准号:21300183
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.81万
-
财政年份:2009
-
负责人:YAMAMOTO Akiko
-
依托单位: