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Prospective study of the prevalence of neuropsychiatric lupus erythematosus (NPSLE) manifestation among patients with SLE in Tochigi prefecture from 2010 to 2012 and the intrathecal production of IL-6, IL-8, IP-10, MCP-1 and G-CSF increase more highly tha

Prospective study of the prevalence of neuropsychiatric lupus erythematosus (NPSLE) manifestation among patients with SLE in Tochigi prefecture from 2010 to 2012 and the intrathecal production of IL-6, IL-8, IP-10, MCP-1 and G-CSF increase more highly tha
2010-2012年栃木县SLE患者神经精神性红斑狼疮(NPSLE)表现患病率及鞘内IL-6、IL-8、IP-10、MCP-1和G-CSF产生增加的前瞻性研究
批准号:
22591081
负责人:
YOSHIO Taku
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

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中文摘要
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英文摘要
1. Prospective study of the prevalence of NPSLE manifestation among patients with SLE in Tochigi from 2010 to 2012: 719 SLE patients were enrolled at the first of studyand 823 enrolled patients were confirmed at the end of study. Prevalence of SLE patient2. The intrathecal production of IL-6, IL-8, IP-10, MCP-1 and G-CSF increase more highly than the serum production in patients with NPSLE: 52 SLE patients, of whom the CSF and serum samples were obtained at the same time, were enrolled. Of 52 SLE patients
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会议论文
An unusual cause of hemichorea-hemiballism in a patient with systemic lupus erythematosus.
系统性红斑狼疮患者偏侧舞蹈症的罕见原因。
DOI: --
发表时间: 2013
期刊: Rheumatol Int
影响因子: 4
作者: [Maruyama A, Nagashima T, Kamata Y, Nagatani K, Murosaki T, Yoshio T, Minota S]
通讯作者: Minota S
Clinical analysis of anti-NR2 glutamate receptor antibodies and interleukin-6 with neuropsychiatric systemic lupus erythematosus
抗NR2谷氨酸受体抗体和白细胞介素6治疗神经精神系统性红斑狼疮的临床分析
DOI: --
发表时间: 2011
期刊: Rheumatology
影响因子: 5.5
作者: [Sato S, Kawashima H, Hoshika A, Yoshio T]
通讯作者: Yoshio T
膠原病の難治性病態とアンメットニーズシンポジウム中枢神経ループス
中枢神经系统狼疮胶原病的难治性病理学及未满足的需求研讨会
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Hiura H, Matsui T, Matsumoto M, Hori Y, Isonishi A, Kato S, Iwamoto T, Mori T, Fujimura Y, 藤枝雄一郎, 菅野仁, 吉尾卓]
通讯作者: 吉尾卓
The intrathecal production of IL-6, IL-8, IP-10, MCP-1 and G-CSFincrease more highly than the serum production in patients with central neuropsychiatric lupus erythematosus (NPSLE).
在中枢神经精神性红斑狼疮 (NPSLE) 患者中,鞘内产生的 IL-6、IL-8、IP-10、MCP-1 和 G-CSF 增加得高于血清产生。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Taku Yoshio, Hiroshi Okamoto, Kazuhiro Kurasawa, Yoshiaki Dei, Shunsei Hirohata, Seiji Minota.]
通讯作者: Seiji Minota.
8
    Association of anti-NMDAR2 antibodies with the pathogenesis of neuropsychiatric systemic lupus erythematosus
    • 批准号:
      15591063
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.86万
    • 财政年份:
      2003
    • 负责人:
      YOSHIO Taku
    • 依托单位:
    海外基金