Tissue-specific redundancy of Hand genes in the cardiac and limbdevelopment
Tissue-specific redundancy of Hand genes in the cardiac and limbdevelopment
批准号:
22591192
负责人:
MAEDA Jun
金额:
$1.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
To investigate the tissue-specific role of genetic redundancy ofHand genes which encode transcription factors necessary to the cardiac and limbdevelopment, we generated genetically engineered mice harboring Hand2 gene replaced byHand1. This study demonstr
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会议论文
心臓形成におけるTbx遺伝子ファミリーを中心とする遺伝子制御 一次元管腔構造から三次元4チャンバー心臓へのリモデリング 流出路発生におけるTBX1の必須な役割
心脏形成中以 Tbx 基因家族为中心的基因调控 从一维管腔结构重塑为三维四腔心脏 TBX1 在流出道发育中的重要作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[土橋 隆俊, 前田 潤, 山岸 千尋, 山岸敬幸]
通讯作者:
山岸敬幸
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