xperimental study for staging strategy establishment of schizophrenia

点击翻译按钮获取中文摘要

In this study, we divided into the progress pathophysiology-stage and the subsequent residual-stage and examined the effects of second generation antipsychotics, mood stabilizers and medicine which stimulate NMDA receptor function in both stages and this research aimed at the establishment of suitable medication according to stages. From the results of this research, medicine which prevents the increases of extracellular glutamate concentration may have blocking effects in the progressive pathophysiology-stage and medicine which stimulate glutamatergic neurotransmission may recover in the subsequent residual-stage.