Non-invasive assessment of hip geometry and biomechanical properties using bone images

使用临床计算机断层扫描（CT）和双能X线吸收法（DXA），髋关节几何形状和结构相关的生物力学性能进行了分析，建立日本妇女数据库，并探讨髋关节几何形状分析的临床实用性，使用骨图像。在这个项目中，我们研究了日本绝经后妇女髋关节几何形状的纵向变化，股骨颈和转子骨折患者髋关节几何形状的特征，以及骨吸收剂（双膦酸盐和活性维生素D3作为骨抗吸收剂，特立派替丁作为骨形成剂）对髋关节几何形状和生物力学特性的有效性。

Using clinical computed tomography (CT) and dual energy X-ray absorptiometry (DXA), hip geometry and structure-related biomechanical properties were analyzed to establish Japanese women database and to investigate clinical usefulness of hip geometry analysis using bone images. In this project, we have investigated longitudinal changes of hip geometry in Japanese postmenopausal women, characteristic of hip geometry in patients with femoral neck and trochanter fracture, and the effectiveness of osteoporotic agents (bisphosphonate and active vitamin D3 as bone anti-resorptive agents, and teriparatid as bone formative agents) on hip geometry as well as biomechanical properties.