Pathological analysis for loss ofmuscle contraction after tendon transfer surgery

肌腱移植术后肌肉收缩丧失的病理分析

• 批准号: 22591658
• 负责人: TAKAHASHI Mitsuhiko
• 金额: $ 2.91万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591658/
• 关键词: 骨格筋; 腱移行; 筋収縮

It is revealed that the tendon transfer surgery in which muscle is stretched leads to an increase in sarcomere number but decrease in physiologic range of the muscle contraction. The active tension of the muscle contraction decreased despite no change in physiologic cross sectional area. It is also revealed that intramuscular connective tissue volume increased, which was thought to be related with the decrease in both physiologic range and in active tension.Intramuscular tendinous tissue had lower extensibility in aged group than that in young group, which further required muscle fiber elongation and sarcomere number increase.

结果表明，肌腱移位手术牵张肌肉，肌节数目增加，但肌肉收缩的生理范围缩小。生理横截面积无变化，但肌肉收缩的主动张力降低。老年组肌腱组织的延伸性低于青年组，这进一步要求肌纤维伸长率和肌节数目增加。

项目成果

Cbl-b is a critical regulator of macrophage activation associated with obesity-induced insulin resistance in mice.

• DOI: 10.2337/db12-0677
• 发表时间: 2013-06
• 期刊: Diabetes
• 影响因子: 7.7
• 作者: Abe T;Hirasaka K;Kagawa S;Kohno S;Ochi A;Utsunomiya K;Sakai A;Ohno A;Teshima-Kondo S;Okumura Y;Oarada M;Maekawa Y;Terao J;Mills EM;Nikawa T
• 通讯作者: Nikawa T

ラット大腿骨骨幹部骨膜の全周性切除が長径成長と骨微細構造に及ぼす影響

大鼠股骨干骨膜环周切除对长轴生长及骨微结构的影响

• 发表时间: 2010
• 期刊: Osteoporosis, Japan
• 作者: 高田信二郎;江西哲也;高橋光彦ほか
• 通讯作者: 高橋光彦ほか

骨格筋の特性が脚延長への適応に与える影響

骨骼肌特性对腿部延长适应的影响

• 发表时间: 2009
• 作者: 杉安謙仁朗;南野勝彦;吉川秀樹;名井陽;Saito A;小笠原邦昭;和田卓郎;高橋光彦
• 通讯作者: 高橋光彦

Expansively hemorrhagic foreign body granuloma at the pelvis caused by microscopic materials

由微观物质引起的骨盆处扩张性出血性异物肉芽肿

• DOI: 10.4236/ojo.2012.21001
• 发表时间: 2012
• 期刊: Open Journal of Orthopedics
• 作者: Morimoto M;Takahashi M;et al
• 通讯作者: et al

Morphological Difference among Finger Metacarpophalangeal Joints

手指掌指关节的形态差异

• 发表时间: 2013
• 作者: Takai M;Takahashi M et al
• 通讯作者: Takahashi M et al