Anti-TNF-alpha antibody attenuates cutaneous ischemia-reperfusion injury in a mouse model of pressure ulcer
Anti-TNF-alpha antibody attenuates cutaneous ischemia-reperfusion injury in a mouse model of pressure ulcer
批准号:
22791062
负责人:
SAITO Yuki
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
In a mouse model of cutaneous ischemia-reperfusion injury, local administration of anti-TNF-α antibody and 1400W inhibited expression of inducible nitric oxide synthase and cytotoxicity of TNF-α From that reason, I suggest that anti-TNF-α antibody treatment might prevent the pressure ulcers.
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