Establishment of a novel spinal cooling method via a pleural cavity for spinal cord protection during thoracoabdominal aneurysm repair.

建立一种通过胸膜腔的新型脊髓冷却方法，用于胸腹动脉瘤修复过程中的脊髓保护。

• 批准号: 22791306
• 负责人: TAKAHASHI Goro
• 金额: $ 2.58万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791306/
• 关键词: 脊髄冷却; 対麻痺予防; 胸腔内冷却; ペルチェ素子; 胸腔内脊髄冷却法; 術中冷却装置; 胸腹部大動脈瘤; 対麻痺; 胸腔内からの脊髄保護法

(1) By the simulation system we have established, we found that it was possible to cool a spinal cord to the target temperature (systemic temperature - 5℃) within 15 to 20 minutes in the constant heat flux condition.(2) We have developed the cooling device with peltier element.(3) With porcine experimental model, we could cool spinal cord to - 2.7℃ compared with systemic temperature within 15minutes in condition with aortic clamping and thermal insulation of a back.

(1)通过我们所建立的仿真系统，我们发现在恒定热流条件下，脊髓在15 ~ 20分钟内可以冷却到目标温度（全身温度- 5℃）。我们研制了珀尔帖元件冷却装置。(3)在猪实验模型中，在主动脉夹持和背部保温的情况下，脊髓在15min内可与体表温度相比冷却至- 2.7℃。