Risk assessment and management of infection with waterborne pathogens via skin route

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Dose-response models for leptospirosis, a typical infectious disease caused by waterborne pathogens via skin route, were developed. Dependencies of Leptospira's infectivity on its serovars and strains and tested animals were discussed with the developed models. Through the discussion we could provide a set of dose-response models available for risk assessment and management of Leptospira infection via skin route. We also tried to develop the risk assessment model for schistosomiasis mekongi as another typical infectious disease. Although the model development did not complete, a framework for schistosomiasis risk assessment was established.