Hormonal regulation of courtship behavior in the urodele amphibian

有尾目两栖动物求爱行为的激素调节

• 批准号: 22770060
• 负责人: HASUNUMA Itaru
• 金额: $ 2.5万
• 依托单位: Toho University (2011)Waseda University (2010)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22770060/
• 关键词: アカハライモリ; 求愛行動; プロラクチン; アルギニンバソトシン; 比較内分泌学; バソトシン受容体; マウスナー細胞; アルギニンバソトシン受容体

It is known that anterior pituitary hormone prolactin(PRL) and posterior pituitary hormone arginine vasotocin(AVT) play important roles in the expression of courtship behavior of the male newt Cynops pyrrhogaster. In this study, we demonstrated that PRL has AVT releasing activity by the organ culture technique and up-regulates the expression of AVT precursor gene. Judging from the result of reporter gene assay using vasopressin V1a receptor antagonist and the localization of AVT V1a-type receptor in the newt brain, it was concluded that the AVT V1a-type receptor is one of the most important receptor in the courtship behavior induced by AVT.

已知垂体前叶激素催乳素（PRL）和垂体后叶激素精氨酸催产素（AVT）在雄性水螅求偶行为的表达中起重要作用。本研究通过器官培养技术证实了PRL具有AVT释放活性，并上调AVT前体基因的表达。从抗利尿激素V1a受体拮抗剂的报告基因检测结果和AVT V1a型受体在蝾螈脑中的定位来看，AVT V1a型受体是AVT诱导求偶行为中最重要的受体之一。

项目成果

Molecular cloning of bullfrog D2 dopamine receptor cDNA: Tissue distribution of three isoforms of D2 dopamine receptor mRNA

• DOI: 10.1016/j.ygcen.2010.04.016
• 发表时间: 2010-08-01
• 期刊: GENERAL AND COMPARATIVE ENDOCRINOLOGY
• 影响因子: 2.7
• 作者: Nakano, Masaki;Hasunuma, Itaru;Kobayashi, Tetsuya
• 通讯作者: Kobayashi, Tetsuya

Expression of genes encoding antimicrobial peptides in the Harderian gland of the bullfrog Lithobates catesbeianus

编码抗菌肽的基因在牛蛙 Lithobates catesbeianus 的哈德氏腺中的表达

• DOI: 10.1016/j.cbpc.2010.05.005
• 发表时间: 2010
• 期刊: Comp Biochem Physiol C Toxicol Pharmacol
• 作者: Hasunuma I;Iwamuro S;Kobayashi T;Shirama K;Conlon JM;Kikuyama S
• 通讯作者: Kikuyama S

ソデフリン前駆体遺伝子の多様性

sodefrin前体基因的多样性

• 发表时间: 2010
• 作者: 蓮沼至;他
• 通讯作者: 他

D2 Dopamine receptor subtype mediates the inhibitory effect of dopamine on TRH-induced prolactin release from the bullfrog pituitary

• DOI: 10.1016/j.ygcen.2010.05.008
• 发表时间: 2010-09-01
• 期刊: GENERAL AND COMPARATIVE ENDOCRINOLOGY
• 影响因子: 2.7
• 作者: Nakano, Masaki;Minagawa, Atsuko;Kobayashi, Tetsuya
• 通讯作者: Kobayashi, Tetsuya

Prolactin increases the synthesis of 7alpha-hydroxypregnenolone, a key factor for induction of locomotor activity, in breeding male Newts

催乳素可增加 7α-羟基孕烯醇酮的合成，这是雄性蝾螈繁殖过程中诱导运动活性的关键因素

• 发表时间: 2010
• 期刊: Endocrinology
• 影响因子: 4.8
• 作者: Haraguchi;S.Koyama;T.Hasunuma;I.;et al
• 通讯作者: et al