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Development of a novel method for quantitative profiling of non-enzymatic post-translational modifications on abundant serum protein

Development of a novel method for quantitative profiling of non-enzymatic post-translational modifications on abundant serum protein
开发一种对丰富血清蛋白进行非酶翻译后修饰定量分析的新方法
批准号:
22790032
负责人:
GOTO Takaaki
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
A novel methodology to profile various non-enzymatic post-translational modifications on serum albumin has been examined. This method is based on mass spectrometry combined with the group-specific immunoaffinity extraction, digestion by proteases with distinct specificity, and complementary data analyses in both positive and negative mode. This strategy can be used for profiling analyses of modifications on albumin in human serum.
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DOI: 10.1021/tx100228q
发表时间: 2010-11-01
期刊: CHEMICAL RESEARCH IN TOXICOLOGY
影响因子: 4.1
作者: [Lee, Seon Hwa, Takahashi, Ryo, Oe, Tomoyuki]
通讯作者: Oe, Tomoyuki
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [村田和之, 後藤貴章, 李宣和, 大江知行, 後藤貴章]
通讯作者: 後藤貴章
血清アルブミンの化学的ストレスによる被修飾部位解析
血清白蛋白中化学应激修饰位点的分析
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [村田和之, 後藤貴章, 李宣和, 大江知行]
通讯作者: 大江知行
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [鈴木健弘, 豊原敬文, 秋山泰利, 竹内陽一, 三島英換, 阿部倫明, 種本雅之, 中山昌明, 伊藤貞嘉, 曽我朋義, 阿部高明, 大江知行, 後藤貴章]
通讯作者: 後藤貴章
The development of a compensatory reading strategy for children with specific reading disorders
  • 批准号:
    26381342
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.0万
  • 财政年份:
    2014
  • 负责人:
    GOTO Takaaki
  • 依托单位:
Developing reading and writing support programs for dyslexic children based on properties of the visual process
  • 批准号:
    24730768
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.41万
  • 财政年份:
    2012
  • 负责人:
    GOTO Takaaki
  • 依托单位:
Research on development of the reading support program to facilitate the reading based on sight-words for children with specific reading disorders
Development of a novel quantification method for simultaneous screeningof bioactive peptides.
  • 批准号:
    20790028
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.83万
  • 财政年份:
    2008
  • 负责人:
    GOTO Takaaki
  • 依托单位:
海外基金