Regulation of Myelination and Glucose Metabolism by Phosphoinositides of Myelination of Myelination and Glucose Metabolism by Phosphoinositides
Regulation of Myelination and Glucose Metabolism by Phosphoinositides of Myelination of Myelination and Glucose Metabolism by Phosphoinositides
批准号:
22790055
负责人:
TAKASUGA Shunsuke
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
We made tissue-specific phosphatidylinositol 3-phosphate 5-kinase (PIPKIII) knockout mice for analyses of myelination in central nervous system and glucose metabolism in muscle. We indicated that essential roles of PIPKIII in oligodendrocytes. And we also found that PIPKIII is a negative regulator of insulin signaling in skeletal muscle.
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Physiological function of phosphatidylinositol -3, 5-bisphosphate in vivo
磷脂酰肌醇-3,5-二磷酸的体内生理功能
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Takasuga S, Sasaki J, Suzuki A, Sasaki T.]
通讯作者:
Sasaki T.
3' phosphatase activity toward PI(3,4)P2 by voltage-sensing phosphatase, VSP
电压感应磷酸酶 (VSP) 对 PI(3,4)P2 的 3 磷酸酶活性
DOI:
--
发表时间:
2012
期刊:
Proc. Natl. Acad. Sci. U. S. A
影响因子:
--
作者:
[Kurokawa T, Takasuga S, Sakata S, Yamaguchi S, Horie S, Homma KJ, Sasaki T & Okamura Y]
通讯作者:
Sasaki T & Okamura Y
DOI:
10.1194/jlr.m002584
发表时间:
2010-06-01
期刊:
JOURNAL OF LIPID RESEARCH
影响因子:
6.5
作者:
[Hiramine, Yasushi, Emoto, Hisayo, Hiramatsu, Ryuji]
通讯作者:
Hiramatsu, Ryuji
DOI:
10.1038/nature09023
发表时间:
2010-05-27
期刊:
NATURE
影响因子:
64.8
作者:
[Sasaki, Junko, Kofuji, Satoshi, Sasaki, Takehiko]
通讯作者:
Sasaki, Takehiko
Elucidation of the mechanism of anticancer activity of the cancer suppressor gene INPP4B
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批准号:18K06623
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2018
-
负责人:TAKASUGA Shunsuke
-
依托单位:
Physiological Function of PI 3-phosphate 5-kinase
-
批准号:20790054
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2008
-
负责人:TAKASUGA Shunsuke
-
依托单位:
海外基金