Syntheses of PET probes of Chinese medicinal plants, and those pharmacokinetics analysis

β-谷甾醇、6-姜辣素、姜黄素、帕特酚内酯、evodiine等用于pet探针前体或标准品合成的化合物，分别从市售中药材半夏、生姜、姜黄、小白菊、枸杞中提取相应粉体，用有机溶剂提取后，采用柱层析法分离得到。成功合成了β-谷甾醇和姜黄素相应的^<11> C-PET探针前体（硼酸酯）。

β-Sitosterol, 6-gingerol, curcumin, parthenolide, and evodiamine, which have used for the synthesis of PET-probe precursors or standard samples, have isolated using column chromatography after the extraction with organic solvents of corresponding powders from the commercially available Chinese medicinal plants : Pinellia tuber, Zingiber siccatum, Curcuma longa, Feverfew, and Evodiae fructus. Corresponding^<11> C-PET probe precursors(boronic acid esters) ofβ-sitosterol and curcumin have successfully synthesized.