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The association between BNP level, NPPB genotype and CVD risk in general Japanese population.

The association between BNP level, NPPB genotype and CVD risk in general Japanese population.
日本普通人群中 BNP 水平、NPPB 基因型与 CVD 风险之间的关联。
批准号：
22790544
负责人：
TAKASHIMA Naoyuki
金额：
$2.41万
依托单位：
Shiga University of Medical Science
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2012
来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22790544/
关键词：
NPPB遺伝子多型脳性ナトリウム利尿ペプチド左室肥大循環器疾患発症予防医学循環器・高血圧社会医学分子疫学

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中文摘要
翻译
脑钠肽（BNP）是心力衰竭的一个临床有用的标志物。在本研究中，我们观察了血浆BNP水平与心电图左心室肥厚之间的显著相关性。然而，我们没有发现心电图左心室肥厚和NPPB基因型之间的显着关联。此外，我们没有发现NPPB基因型与未来心血管疾病风险之间的任何显着关联。因此，需要进一步的研究来检查CVD风险和NPPB基因型之间的关联。
英文摘要
Brain natriuretic peptide (BNP) is a clinical useful marker forheart failure. In the present study, we observed the significant association between plasma BNP levels and electrocardiographic left ventricular hypertrophy. However, we did not find the significant association between electrocardiographic left ventricular hypertrophy and the NPPB genotype. Furthermore, we did not find any significant association between the NPPB genotype and future cardiovascular disease risk. Therefore, it is needed for further research to examine the association between CVD risk and the NPPB genotype.
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The association between functional disability and lifestyle-related factors among the general population, and the long-term functional prognosis of stroke.
Investigation of genetic risk factors for cardiovascular disease in general population.
  • 批准号：
    20790424
  • 项目类别：
    Grant-in-Aid for Young Scientists (B)
  • 资助金额：
    $2.75万
  • 财政年份：
    2008
  • 负责人：
    TAKASHIMA Naoyuki
  • 依托单位：
    Shiga University of Medical Science
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