Effects of a high-fat or a high-sucrose diet on ultraviolet B irradiation-induced carcinogenesis and tumor growth in hairless mice.

高脂肪或高蔗糖饮食对紫外线 B 照射诱导的无毛小鼠致癌和肿瘤生长的影响。

• 批准号: 22790619
• 负责人: SUMIYOSHI Maho
• 金额: $ 2.58万
• 依托单位: Ehime University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22790619/
• 关键词: 発癌; 紫外線B波; 肥満; 耐糖能異常

In this study, I examined the effects of a high-fat diet or a high-sucrose diet on ultraviolet(UV) B irradiation-induced carcinogenesis and tumor growth in melanin-possessing hairless mice. UVB irradiation-induced carcinogenesis and tumor growth in high-fat diet-fed mice were accelerated compared to those in control dietor high-sucrose diet-fed mice.

在这项研究中，我检查了高脂肪饮食或高糖饮食对紫外线（UV）B辐射诱导的黑色素无毛小鼠的致癌作用和肿瘤生长的影响。与对照组或高糖组小鼠相比，高脂组小鼠UVB辐射诱发的致癌作用和肿瘤生长加速。