Epigenomic analysis of DNA methylation pattern in cardiomyocyte development and evaluation of stem cell differentiation methods.
Epigenomic analysis of DNA methylation pattern in cardiomyocyte development and evaluation of stem cell differentiation methods.
批准号:
22790730
负责人:
ODA Mayumi
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
Epigenome is thought to represent the developmental potential of given cells. However, it has been unknown where is the genomic regions that define the ability of cells, like stemness or spectrum of cell-type specific potentials. In this study, we sought
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Cell Type-specific Gene Body DNA Hypomethylationin Cardiac Genes Contributes to Transcriptional Efficiency in CardiomyocyteMaturation
心脏基因中细胞类型特异性基因体 DNA 低甲基化有助于心肌细胞成熟的转录效率
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Mayumi Oda, Shinji Makino, Hirokazu Enomoto, Kojiro Yae, Ruri Kaneda, Shinsuke Yuasa, and Keiichi Fukuda.]
通讯作者:
and Keiichi Fukuda.
DNA Methylation Changes in The b-MHC Locus Mediate Gene Regulation by Antisense RNA in Postnatal Cardiomyocyte Development.
b-MHC 位点的 DNA 甲基化变化介导出生后心肌细胞发育中反义 RNA 的基因调控。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Mayumi Oda, Shinji Makino, Shinsuke Yuasa, Sung Han Yoon, Yuta Higashikuse, Kojiro Yae, Ruri Kaneda, Mitsushige Murata, Motoaki Sano, John M. Greally and Keiichi Fukuda]
通讯作者:
John M. Greally and Keiichi Fukuda
DNA Methylation Changes in the b-MHC Locus Mediate Gene Regulation by Antisense RNA in Mouse Postnatal Cardiomyocyte Development
b-MHC 位点 DNA 甲基化变化介导小鼠产后心肌细胞发育中反义 RNA 的基因调控
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Oda M, Makino S, Fukuda K]
通讯作者:
Fukuda K
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研究地图
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Cell Type-specific Gene Body DNA Hypomethylationin Contributes to Transcriptional Efficiency in Cardiomyocyte Maturation.
细胞类型特异性基因体 DNA 低甲基化有助于心肌细胞成熟的转录效率。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Mayumi Oda, Shinji Makino, Hirokazu Enomoto, Kojiro Yae, Ruri Kaneda, Shinsuke Yuasa and Keiichi Fukuda]
通讯作者:
Shinsuke Yuasa and Keiichi Fukuda
共 14 条
Mechanism for cardiomyocyte-specific nuclear architecture and disease development by dynamic DNA demethylation system.
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批准号:18K08085
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2018
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负责人:ODA Mayumi
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依托单位:
Optimization of direct reprograming methods by understanding the epigenomic features of descendant cell types.
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批准号:25660256
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2013
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负责人:ODA Mayumi
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依托单位:
Coordinated epigenetic regulation of cell type-specific genes and chronic disease development in cardiomyocytes.
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批准号:24689037
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$7.65万
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财政年份:2012
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负责人:ODA Mayumi
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依托单位:
海外基金