Analysis of biological function of recombinase A in Streptococcus mutansquorum sensing

变形链球菌产生3种类型的葡糖基转移酶（GTF），它们与重组酶A（RecA）蛋白的协同作用是细胞粘附所必需的，重组酶A（RecA）蛋白是同源重组所必需的。gtf和gtfC基因的序列测定表明，在光滑菌落中缺失了约3500 bp的区域。变种人这些结果表明，DNA重组和表型的变化，发生通过摄取胞外RecA可能有一个信号转导系统，涉及生物膜的形成在S。变种人

Streptococcus mutansproduces 3 types of glucosyltransferases (GTFs), whose cooperative action is essential for cellular adhesion, with the recombinase A (RecA) protein required for homologous recombination. Determination of the sequences of the gtfBand gtfCgenes showed that an approximately 3500-bp region was deleted in the smooth colonies of S. mutans. These results suggest that DNA recombination and phenotypic changes that occur through uptake of extracellular RecA may have a relationship with the signal transduction system involving biofilm formation in S. mutans.