Establishment of periodontal ligament (PDL) cells derived from deciduous teeth and periodontal tissue regeneration with PDL cells.
Establishment of periodontal ligament (PDL) cells derived from deciduous teeth and periodontal tissue regeneration with PDL cells.
批准号:
22592296
负责人:
HASEGAWA Tomokazu
金额:
$2.83万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
我们建立了人乳牙牙周膜细胞的克隆细胞系。SH 9细胞具有向成骨细胞和脂肪细胞分化的能力。基质细胞衍生因子-1 α(SDF-1 α)在间充质干细胞和内皮祖细胞的迁移中起重要作用。我们报道了SDF-1在SH 9细胞中的表达受多种细胞因子的调节.
英文摘要
We established clonal cell lines of periodontal ligament cells derived from human deciduous teeth immortalized by hTERT gene transfer. SH 9 cells showed the ability of differentiation into both osteoblasts and adipocytes. Stromal cell-derived factor-1α(SDF-1) has important roles in migration of mesenchymal stem cells and endothelial progenitor cells. We reported that SDF-1 expression in SH 9 cells was regulated by various cytokines.
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DOI:
10.1007/978-4-431-54070-0
发表时间:
2012
期刊:
影响因子:
--
作者:
[K. Sasaki;O. Suzuki;N. Takahashi;P. Stashenko;M. Cambridge]
通讯作者:
K. Sasaki;O. Suzuki;N. Takahashi;P. Stashenko;M. Cambridge
Differential effects of TGF-β1 and FGF-2 on SDF-1α expression in human periodontal ligament cells derived from deciduous tooth in vitro
TGF-β1和FGF-2对人乳牙源性牙周膜细胞SDF-1α表达的差异影响
DOI:
--
发表时间:
2012
期刊:
Int J Mol Med
影响因子:
5.4
作者:
[Hasegawa T, et al]
通讯作者:
et al
ヒト乳歯歯根膜細胞におけるSDF-1の発現調節機構
人乳牙牙周膜细胞SDF-1表达的调控
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[長谷川智一, 帖佐直幸, 西平宗功, 石崎 明, 田中光郎]
通讯作者:
田中光郎
Stage-dependent suppression of the formation of dentin-resorbing multinuclear cells with MIF in vitro
体外 MIF 对牙本质吸收多核细胞形成的阶段依赖性抑制
DOI:
10.3892/etm.2011.362
发表时间:
2011
期刊:
Experimental and Therapeutic Medicine
影响因子:
2.7
作者:
[Kikuiri T, Yoshimura Y, Tabata F, Hasegawa T, Nishihira J, Shirakawa T]
通讯作者:
Shirakawa T
ヒト永久歯歯根膜細胞におけるSDF-1の発現
SDF-1在人恒牙牙周膜细胞中的表达
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[浅川剛吉, 帖佐直幸, 長谷川智一, 浅川麻美, 石崎 明, 田中光郎]
通讯作者:
田中光郎
共 31 条
Effect of CCL11 derived from deciduous tooth on pulp and root resorption
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批准号:20K10205
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2020
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负责人:HASEGAWA Tomokazu
-
依托单位:
homeostatic regulation and regeneration of periodontal ligament tissues
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批准号:16K11804
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2016
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负责人:HASEGAWA Tomokazu
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依托单位:
Study of periodontal ligament tissue function about maintaining homeostasis and regeneration in periodontal tissues, and development of new regeneration therapy in periodontal tissues.
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批准号:25463182
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2013
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负责人:HASEGAWA Tomokazu
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依托单位:
Analysis of periodontal ligament cells derived from permanent teeth and primary teeth on tooth root resorption.
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批准号:18592239
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.49万
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财政年份:2006
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负责人:HASEGAWA Tomokazu
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依托单位:
Analysis of genetic risk factors in periodontal diseses ― Effect of cellular aging on damage of cells ―
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批准号:12557178
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.85万
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财政年份:2000
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负责人:HASEGAWA Tomokazu
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依托单位:
Establishment of Human Fibroblasts deribed from Dental Pulp Tissues of Primary Teeth and Permanent Teeth, and Development of Systems of Cytotoxicity Tests for Dental Materials
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批准号:08672378
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:1996
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负责人:HASEGAWA Tomokazu
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依托单位:
海外基金