Meteorological factors associated with exacerbation of the disease and reduced quality of life in patients with respiratory disease

我们的发现，在夏季，如下：第一，前一天的日最低温度（或日平均温度）与高湿球地球仪温度（WBGT值为28摄氏度或更高，即，日本生物统计学会建议的中暑高度警戒级别）。其次，夜间WBGT最低值与接受长期氧疗患者呼吸困难风险增加相关。最后，病例交叉设计显示COPD急性加重与气象因素之间无统计学显著相关性，因为我们的研究受试者因急性加重而住院的数量较少。

Our findings, in summer, were as follows: Firstly, daily minimum temperature (or daily average temperature) on previous day were associated with high wet-bulb globe temperature (WBGT values of 28 degrees C or higher, i.e., level of extreme caution for heatstroke, proposed by Japanese Society of Biometeorology) during nighttime (from 0:00 to 6:00). Secondly, minimum WBGT values during nighttime were associated with an increased risk of having dyspnea in patients receiving long term oxygen therapy. Finally, case-crossover design showed no statistically significant association between COPD exacerbation and meteorological factors, because we had a small number of hospitalizations of study subjects for the exacerbation.