Economic benefit of Helicobacter pylori screening and eradication treatment for the prevention of gastric cancer

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The purpose of this study is to predict the economic benefit of an H. pylori eradication strategy as a method to prevent of gastric cancer. Using data in the literature and statistics such as patient survey and basic survey on wage structure, the number of those who developed gastric cancer by H. pylori was estimated and the cost benefit analysis was done. When the response rates of screening and eradication treatment are set at (30%, 60%), (20%, 40%), and (40%, 70%), the cost benefit ratios would be 0.9,1.6 and 0.7 respectively. When the response rates are high, the cost would be huge but would be recovered very quickly. The infection rate of H. pylori is gradually decreasing in younger people and it is necessary to consider the trend in the number of the infected people, the response rates of screening and that of eradication treatment for the economic evaluation.