Efficacy of Computer-Assisted Measurements for Retinal Artery and Vein in relation to Risk of Stroke

计算机辅助测量视网膜动脉和静脉与中风风险相关的功效

• 批准号: 22659135
• 负责人: KITAMURA Akihiko
• 金额: $ 2.04万
• 依托单位: 財団法人大阪府保健医療財団 大阪がん循環器病予防センター (2012)Osaka Medical Center for Health Science and Promotion (2010-2011)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659135/
• 关键词: 健康診断; 眼底検査; 脳卒中予防; 穿通枝系梗塞; 網膜血管径; コホート内症例対照研究

Using a quantitative retinal image analysis, we measured the diameter of retinal artery and vein in individuals participated in health screening program in Osaka, Akita, and Ibaraki. Then, we examined the association of these quantitative measures in relation to risk of developing stroke. Retinal arteriolar narrowing was associated with increased risk of stroke; compared with individuals with larger retinal arteriolar diameter, those with smaller retinal arteriolar diameter had 4 to 5-fold higher risk of stroke. This association was partially independent of traditional Scheie’s classification of retinal arteriolosclerosis. The current findings suggest that the predictive ability of the fundus assessment in relation to stroke risk may be improved by using the proposed quantitative retinal vessels in addition to the Scheie’s classification, which is widely used at health checkup in Japan.

利用定量视网膜图像分析，我们测量了在大坂，秋田和茨木参加健康筛查计划的个人的视网膜动脉和静脉的直径。然后，我们研究了这些定量指标与发生卒中风险的相关性。视网膜小动脉狭窄与中风风险增加有关;与视网膜小动脉直径较大的个体相比，视网膜小动脉直径较小的个体中风风险高4至5倍。这种关联部分独立于传统的Scheie视网膜小动脉硬化分类。目前的研究结果表明，眼底评估中风风险的预测能力可能会得到改善，通过使用拟议的定量视网膜血管除了Scheie的分类，这是广泛使用的健康检查在日本。

项目成果

眼底検査-健診時の基礎知識-

眼底检查-体检基础知识-

• 发表时间: 2010
• 期刊: MEDICAL TECHNOLOGY
• 作者: 岡田睦美;宇野充子;永野英子;北村明彦;飯田稔;石川善紀
• 通讯作者: 石川善紀