Research of molecular mechanisms regulating responsiveness to chondrogenic cytokines by intracellular trafficking protein SNX

细胞内转运蛋白SNX调节软骨细胞因子反应性的分子机制研究

• 批准号: 22659265
• 负责人: TAKESHITA Katsushi
• 金额: $ 2.11万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659265/
• 关键词: 骨; 軟骨代謝学; 骨・軟骨代謝学; 軟骨誘導リガンド

SNX19, a member of the SNX family of intracellular trafficking proteins, was highly expressed in chondrocytes through their differentiation. SNX19 enhanced the production of cartilage matrix like Col2a1 ; however, the molecular mechanism underlying the enhancement was still unrevealed

SNX19是SNX家族细胞内转运蛋白的一员，通过软骨细胞的分化，SNX19在软骨细胞中高表达。SNX19可促进COL2a1等软骨基质的生成，但其分子机制尚不清楚

项目成果

Reproducibility of measurements of thumb abduction.

拇指外展测量的再现性。

• 发表时间: 2010
• 期刊: Hand Surg
• 作者: Muraki S;Akune T;Oka H;Mabuchi A;En-yo Y;Yoshida M;Saika A;Suzuki T;Yoshida H;Ishibashi H;Tokimura F;Yamamoto S;Nakamura K;Kawaguchi H;Yoshimura N;Yoshimura N;Muraki S;Muraki S;Oka H;Itoh S
• 通讯作者: Itoh S

Osteochondral autograft for medial femoral condyle chondral lesions in a patient with multiple epiphyseal dysplasia : long-term result

自体骨软骨移植治疗多发性骨骺发育不良患者股骨内侧髁软骨病变：长期结果

• 发表时间: 2011
• 期刊: J Orthop Sci
• 影响因子: 1.7
• 作者: Taketomi S;Hiraoka H;Nakagawa T;Miyamoto Y;Kuribayashi S;Fukuda A;Takeda H;Fukai A;Hirota J;Nakajima K;Haga N;Nakamura K
• 通讯作者: Nakamura K

Predictability of surgical correction of scoliosis by supine, side-bending fulcrum and traction radiographs

通过仰卧、侧弯支点和牵引X线照片矫正脊柱侧弯手术的可预测性

• 发表时间: 2010
• 作者: Takeshita K;et al
• 通讯作者: et al

Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice

• DOI: 10.1002/art.33324
• 发表时间: 2012-01-01
• 期刊: ARTHRITIS AND RHEUMATISM
• 作者: Fukai, Atsushi;Kamekura, Satoru;Kawaguchi, Hiroshi
• 通讯作者: Kawaguchi, Hiroshi

New parameters to represent the position of the aorta relative to the spine for pedicle screw placement

• DOI: 10.1007/s00586-010-1298-9
• 发表时间: 2010-05-01
• 期刊: EUROPEAN SPINE JOURNAL
• 影响因子: 2.8
• 作者: Takeshita, Katsushi;Maruyama, Toru;Nakamura, Kozo
• 通讯作者: Nakamura, Kozo