The study of molecular basis underlying the motor control in the basal ganglia.

了解由大脑组成的神经群的性质和神经网络的构成，对认识脑功能的多样性和认识神经疾病至关重要。然而，在包括情绪和运动控制在内的高级脑功能中，仍然缺乏全局分析，以揭示哪种神经元群表现出独特的基因表达模式，与几种神经元群通过何种分子机制相互作用，以及产生何种神经功能。在本研究中，我分析了苍白球的基因表达模式，苍白球作为基底神经节介导的情绪和运动控制的输出装置。

It is essential to understand the property of neural population consisting of the brain and the constitution of neural network in familiarization with the variety of brain function and the nerve disease. However, in the higher brain function including the mood and motor control, it still lacks the global analysis to reveal what kinds of neuronal populations showing the unique gene expression patterns interplay with several neuronal populations using what molecular mechanisms, and which neural function was generated. In this study, I analyzed the gene expression pattern in the globus pallidus, as an output device of the basal ganglia mediated mood and motor control.