Cerebellar microstructures and their electrophysiological and functional properties

通过腺病毒转染，Channelrhodopsin-2仅在具有相同生日的特定浦肯野细胞上表达。由于chr2阳性的浦肯野细胞在小脑皮层内形成了显著的微结构，我提出了一种局部激活相同结构内的浦肯野细胞的方法，并研究了其对小脑网络的影响。我也将同样的方法应用于老鼠的视觉皮层。

Using adenoviral transfection, Channelrhodopsin-2 was expressed only onto specific Purkinje cells with the same birthday. Since the ChR2-positive Purkinje cells make remarkable microstructures within cerebellar cortex, I made a method to locally activate the Purkinje cells within the same structure and studied the effects on cerebellar network. I also applied the same method to mouse visual cortex.