Control of neural circuit formation using light-regulated adenylyl cyclase in vivo.
Control of neural circuit formation using light-regulated adenylyl cyclase in vivo.
使用体内光调节腺苷酸环化酶控制神经回路形成。
批准号：
22700410
负责人：
ISHII Tomohiro
金额：
$2.58万
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2010
资助国家：
日本
项目状态：
已结题
起止时间：
2010 至 2011
中文摘要
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英文摘要
To understand how cAMP is used to exert various functions in mouse olfactory sensory neurons(OSNs), we generated transgenic mice in which PAC, photo-activated adenylate cyclase, is expressed under the control of the mouse olfactory receptor promoter. PAC was detected throughout OSN including dendrites and axons, allowing local activation of PAC. We are currently analyzing the function of cAMP in neural circuit formation by regulating PAC activity using light.
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会议论文
ポリペプチド、単離された核酸、組み換えベクター、遺伝子導入キット、形質転換体、および細胞内カルシウムシグナルの調整方法
用于调节细胞内钙信号的多肽、分离的核酸、重组载体、基因转移试剂盒、转化体和方法
用于调节细胞内钙信号的多肽、分离的核酸、重组载体、基因转移试剂盒、转化体和方法
DOI：
--
发表时间：
2012
期刊：
影响因子：
--
作者：
[]
通讯作者：
DOI：
10.1016/j.mcn.2010.11.002
发表时间：
2011-02-01
期刊：
MOLECULAR AND CELLULAR NEUROSCIENCE
影响因子：
3.5
作者：
[Ishii, Tomohiro, Mombaerts, Peter]
通讯作者：
Mombaerts, Peter
Identification of adrenogonadal progenitor cells in the gonads which can be reprogrammed into adrenal steroidogenic cells
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批准号：19K08987
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$2.75万
-
财政年份：2019
-
负责人：ISHII Tomohiro
-
依托单位：
Near-infrared optogenetic tools
-
批准号：18K05549
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$2.83万
-
财政年份：2018
-
负责人：ISHII Tomohiro
-
依托单位：
Neural network regulating olfactory functions in mice
-
批准号：15K06735
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$3.33万
-
财政年份：2015
-
负责人：ISHII Tomohiro
-
依托单位：
Clinical evaluation of removable partial denture prosthesis treatment based on the coordination of the jaw and neck muscle activity and the jaw and head movements.
-
批准号：25463028
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$2.66万
-
财政年份：2013
-
负责人：ISHII Tomohiro
-
依托单位：
Transcriptome analysis of steroidogenic cells in knockout mice lacking steroidogenic acute regulatory protein
-
批准号：23591516
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$3.33万
-
财政年份：2011
-
负责人：ISHII Tomohiro
-
依托单位：
The role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by BAC transgenesis in vivo
-
批准号：20591231
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$2.91万
-
财政年份：2008
-
负责人：ISHII Tomohiro
-
依托单位：
Targeted expression of enhanced green fluorescent protein to steroidogenic cells expressing steroidogenic acute regulatory protein by bacterial artificial chromosome transgenesis in vivo
-
批准号：18591167
-
项目类别：Grant-in-Aid for Scientific Research (C)
-
资助金额：$2.52万
-
财政年份：2006
-
负责人：ISHII Tomohiro
-
依托单位：
海外基金
