The role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by BAC transgenesis in vivo
The role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by BAC transgenesis in vivo
批准号:
20591231
负责人:
ISHII Tomohiro
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
The present study clarified the mechanism of steroidogenic acute regulatory protein (StAR) that transfers cholesterol from the outer to the inner mitochondrial membrane in the first step of acute steroidogenesis. It demonstrated the important role of mitochondrial entry of StAR by its mitochondrial targeting signal on the function of the StAR in vivo.
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专著(0)
科研奖励(0)
会议论文
DOI:
10.1210/me.2007-0493
发表时间:
2008-04
期刊:
Molecular endocrinology
影响因子:
--
作者:
[G. Sasaki;T. Ishii;P. Jeyasuria;Y. Jo;Assaf Bahat;J. Orly;T. Hasegawa;K. Parker]
通讯作者:
G. Sasaki;T. Ishii;P. Jeyasuria;Y. Jo;Assaf Bahat;J. Orly;T. Hasegawa;K. Parker
Steroidogenic acute regulatory protein のin vivo における機能解析
类固醇生成急性调节蛋白的体内功能分析
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[久保和泰, 山本幸代, 川越倫子, 後藤元秀, 荒木俊介, 土橋一重, 楠原浩一, 石井智弘]
通讯作者:
石井智弘
Identification of adrenogonadal progenitor cells in the gonads which can be reprogrammed into adrenal steroidogenic cells
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批准号:19K08987
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2019
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负责人:ISHII Tomohiro
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依托单位:
Near-infrared optogenetic tools
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批准号:18K05549
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2018
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负责人:ISHII Tomohiro
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依托单位:
Neural network regulating olfactory functions in mice
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批准号:15K06735
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2015
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负责人:ISHII Tomohiro
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依托单位:
Clinical evaluation of removable partial denture prosthesis treatment based on the coordination of the jaw and neck muscle activity and the jaw and head movements.
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批准号:25463028
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2013
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负责人:ISHII Tomohiro
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依托单位:
Transcriptome analysis of steroidogenic cells in knockout mice lacking steroidogenic acute regulatory protein
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批准号:23591516
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:ISHII Tomohiro
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依托单位:
Control of neural circuit formation using light-regulated adenylyl cyclase in vivo.
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批准号:22700410
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
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财政年份:2010
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负责人:ISHII Tomohiro
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依托单位:
Targeted expression of enhanced green fluorescent protein to steroidogenic cells expressing steroidogenic acute regulatory protein by bacterial artificial chromosome transgenesis in vivo
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批准号:18591167
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.52万
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财政年份:2006
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负责人:ISHII Tomohiro
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依托单位:
海外基金