Movement initiation-locked brain activity can predict future movement instability.

运动启动锁定的大脑活动可以预测未来运动的不稳定性。

• 批准号: 22700596
• 负责人: ARAMAKI Yu
• 金额: $ 2.5万
• 依托单位: Chukyo University (2011)Nagoya Institute of Technology (2010)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22700596/
• 关键词: 大脳基底核; 両手運動; fMRI; 脳信号; 脳機能イメージング; 運動エラー; 脳活動

In periodic bimanual movements, anti-phase-coordinated patterns often change into in-phase patterns suddenly and involuntarily. Because behavior in the initial period of a sequence of cycles often does not show any obvious errors, it is difficult to predict subsequent movement errors in the later period of the cyclical sequence. Here, we evaluated performance in the later period of the cyclical sequence of bimanual periodic movements using human brain activity measured with functional magnetic resonance imaging as well as using initial movement features. Eighteen subjects performed a 30 s bimanual finger-tapping task. Correlation analysis revealed that the difference in the anterior putamen activity during antiphase compared within-phase tapping conditions was strongly correlated with future instability as measured by the mean absolute deviation of the left-hand intertap interval during antiphase movements relative to in-phase movements(r_0.81). Our results suggest that initiation-locked transient activity of the anterior putamen can be used to predict future motor performance.

在周期性双手动作中，反相协调模式常常突然地、不自主地转变为同相模式。由于在一系列周期的初始阶段的行为通常不显示任何明显的错误，因此很难预测周期序列后期的后续运动错误。在这里，我们评估的表现，在后期的周期性序列的双手周期性运动使用人类大脑活动测量功能磁共振成像，以及使用初始运动功能。18名受试者进行了30秒的双手手指敲击任务。相关性分析表明，前壳核活动的差异，在反相内相轻敲条件下相比，与未来的不稳定性，测量的平均绝对偏差的左手intertap间隔在反相运动相对于同相运动（r_0.81）。我们的研究结果表明，启动锁定的前壳核的瞬态活动可以用来预测未来的运动性能。

项目成果

Decrease in effective connectivity from cerebellum to primary motor cortex during bimanual movements

双手运动期间小脑到初级运动皮层的有效连接减少

• 发表时间: 2010
• 作者: Aramaki Y;Kochiyama T;Osu R;Nozaki D
• 通讯作者: Nozaki D

大脳基底核活動モニタリングによる脳負荷評価法の開発

通过监测基底神经节活动开发脑负荷评估方法

• 发表时间: 2011
• 作者: Aramaki Y;Osu R;Sadato N.;荒牧勇
• 通讯作者: 荒牧勇

Movement Initiation-Locked Activity of the Anterior Putamen Predicts Future Movement Instability in Periodic Bimanual Movement

• DOI: 10.1523/jneurosci.4473-10.2011
• 发表时间: 2011-07-06
• 期刊: JOURNAL OF NEUROSCIENCE
• 影响因子: 5.3
• 作者: Aramaki, Yu;Haruno, Masahiko;Sadato, Norihiro
• 通讯作者: Sadato, Norihiro

Modification of effective connectivity of cerebro-cerebellar loop by movement of the opposing limb

通过对侧肢体的运动来改变脑小脑环的有效连接

• 发表时间: 2010
• 作者: Aramaki Y.;Kochiyama T.;Osu R.;Nozaki D.
• 通讯作者: Nozaki D.

Modification of effective connectivity of cerebro-cerebellar loop by movement of the opposing limb.

通过对侧肢体的运动来改变脑-小脑环的有效连接。

• 发表时间: 2010
• 作者: Aramaki Y.;Kochiyama T.;Osu R.;Nozaki D.
• 通讯作者: Nozaki D.