The effect of work of breathing on aerobic performance and active muscles oxygenation level in hypoxia.

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The present study was tried to investigated whether respiratory muscles activity alter in hypobaric hypoxic condition, and whether it affects to thigh muscle issue oxygenation level. The results were as follow, 1) In hypoxic condition, work of breathing (WOB) was higher than in normoxia and, the magnitude of the pulmonary ventilation (VE) in hypoxia significantly correlated to the tissue oxygenation level during maximal exercise. 2) WOB during exercise with helium oxygen mixture gases (simulated hypobaric condition) inhalation was lower than in normal air inhalation despite of increase in VE and, it affected to aerobic exercise performance. 3) The improvement of respiratory muscles strength by inspiratory muscle training improved the aerobic exercise performance.