Development of the affinity matrix for comprehensive analysis of ligand- binding proteins
Development of the affinity matrix for comprehensive analysis of ligand- binding proteins
批准号:
22710219
负责人:
KURAMOCHI Kouji
金额:
$2.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Bioactive compounds such as drugs and toxins generally show their activities by interacting with their specific receptors. In this study, we explored the binding proteins of perfluorooctanesulfonic acid, which is a man-made fluorosurfactant and global pollutant, and apigenin, which is a natural product belonging to the flavone. We also developed a novel affinity matrix for purifying the binding proteins of bioactive compounds.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
固相合成とファージディスプレイ法を組み合わせたPFOS結合タンパク質の探索
结合固相合成和噬菌体展示方法寻找 PFOS 结合蛋白
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[宮野友香, 水品善之, 他, 全21名]
通讯作者:
全21名
光固定化とファージディスプレイ法を融合した薬剤結合タンパク質の探索
结合光固定化和噬菌体展示方法寻找药物结合蛋白
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Takano N, Yamamoto T, Adachi T, and Suematsu M, 倉持 幸司]
通讯作者:
倉持 幸司
Innovative approach to identify cellular targets of the anti-inflammatory flavonoid apigenin
识别抗炎类黄酮芹菜素细胞靶标的创新方法
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kajimura M, Fukuda R, Bateman RM, Yamamoto T, and Suematsu M, Daniel Arango]
通讯作者:
Daniel Arango
Exploration of the binding proteins of perfluorooctane sulfonate by a T7 phage display screen
通过 T7 噬菌体显示屏探索全氟辛烷磺酸的结合蛋白
DOI:
10.1016/j.bmc.2012.05.016
发表时间:
2012
期刊:
Bioorg. Med. Chem.
影响因子:
--
作者:
[Miyano Y, Tsukuda S, Sakimoto I, Takeuchi R, Shimura S, Takahashi N, Kusayanagi T, Takakusagi Y, Okado M, Matsumoto Y, Takakusagi K, Takeuchi T, Kamisuki S, Nakazaki A, Ohta K, Miura M, Kuramochi K, Mizushina Y, Kobayashi S, Sugawara F, Sakaguchi K.]
通讯作者:
Sakaguchi K.
DOI:
10.1073/pnas.1303726110
发表时间:
2013-06-11
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Arango, Daniel, Morohashi, Kengo, Doseff, Andrea I.]
通讯作者:
Doseff, Andrea I.
共 8 条
Bioinspired synthesis and structural elucidation of natural naphthoquinone dimers
-
批准号:25850083
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2013
-
负责人:KURAMOCHI Kouji
-
依托单位:
海外基金