Longitudinal study for postpartum depression(PPD): establishment of collaborative community system for the early detection and intervention of PPD

背景：据报道，全世界一般人群中产后抑郁症（PPD）的患病率为10%至15%。然而，产妇年龄与PPD出现的相关性尚未得到很好的记录。为了解决这个问题，我们使用滨松母婴出生队列（HBC）估计了PPD的年龄特异性3个月累积发病率。方法：采用一项正在进行的出生队列研究，我们连续招募了怀孕中期的孕妇（n=723），这些孕妇预计将在我们的两个研究地点之一分娩。产后抑郁症妇女的定义是在分娩后3个月使用爱丁堡产后抑郁量表得分9分或更高。结果：在675名参与调查的产妇中，发现100名妇女患有产后抑郁症；产后3个月PPD的累计发病率为14。8%。具体年龄估计为20人。少于25年的占8%，14。25到29年的2%，11。30到34年5%，17年。为9%。≧35年。logistic回归分析发现，年龄≥35岁的产妇患PPD的OR值增加1。7，在控制了伴侣的年龄、胎次和家庭收入后，这一结果仍然显著。局限性：虽然样本具有代表性，但样本量不大。结论：PPD的累积发病率在不同年龄组之间存在显著差异，其中高龄组的发病率最高。在年龄≥35岁的产妇中，PPD的累积发病率达到高峰，然而，升高的估计值与伴侣的年龄、胎次或家庭年收入无关。

BACKGROUND : The prevalence of postpartum depression(PPD) in the general population has been reported to be 10% to 15% worldwide. However, the relevance of age of the parturients to the emergence of PPD has not been well documented. To address this, we estimated the age-specific 3-month cumulative incidence of PPD using the Hamamatsu Birth Cohort for Mothers and Children(HBC).METHODS : Using an ongoing birth cohort study, we consecutively enrolled parturients who were at mid-pregnancy(n=723) and were expected to give birth at either of our two research sites. Women with PPD were defined as those scoring 9 points or higher using the Edinburgh Postnatal Depression Scale 3 months after childbirth.RESULTS : Among 675 participating parturients, 100 women were found to have PPD ; the cumulative incidence of PPD over the 3 months after childbirth was 14. 8%. The age-specific estimates were 20. 8% for<25 years, 14. 2% for 25 to 29 years, 11. 5% for 30 to 34 years, and 17. 9% for.≧35 years. In the logistic regression analysis, the increased OR for having PPD among parturients aged≧35 years was 1. 7, which remained significant after controlling for age of partner, parity, and household income.LIMITATIONS : Although the sample was representative, the sample size was modest.CONCLUSION : The cumulative incidence of PPD was significantly different across age groups, with the highest estimates in the advanced age band. There was a peak of cumulative incidence of PPD among parturients aged≧35 years, however, the heightened estimate was not accounted for by the age of the partner, parity, or annual household income.