Function of spinal neural circuit for generating muscle activities

点击翻译按钮获取中文摘要

In monkeys performing precision grip task, we recorded activity from the cervical spinal cordsimultaneously with electromyographic (EMG) activity from hand and arm muscles during the task. Most PreM-INs (23/25) displayed movement-related firing rate modulations: 11 had phasic followed by tonic facilitation (p+t+); 4 were pure phasic; 4 were pure tonic; and 4 were deactivated, while their target muscles consistently had p+t+ activity (65/66 muscles). Results indicated that several neural pathway could be mediated by the spinal PreM-INs makes a significant contribution to the control of precision grip in primates. For detecting the descending signal mediated by spinal Ins, we identified 251 M1 and 90 rubrospinal neurons, and extracted muscle synergies using non-negative matrix factorization from the EMG signals. Clustering analysis of the PreM connection patterns of the populations indicate each PreM population can provide a neuronal underpinning of muscle synergies in contrasting ways.