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Evolution of Eye as sensory organ

眼睛作为感觉器官的进化

基本信息

批准号：
23370098
负责人：
IKEO KAZUHO
金额：
$ 12.15万
依托单位：
National Institute of Genetics
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2011
资助国家：
日本
起止时间：
2011-04-01 至 2014-03-31
项目状态：
已结题

项目摘要

To understand the process and origin of various eyes, I conducted comparative evolutionary study by using next generation sequence technology. For the purpose, I took two different types of Jellyfish with and without eye and also dinoflagellate with different types of lens eye. RNA-seq by next generation sequence technology performed collection of gene expression profiles of the species. The visual pigment of dinoflagellate showed the similarity with bacterial pigment and it suggests the origin of their eye-like structure related to bacterial origin. The other side, the result of jellyfish showed the molecules related their lens development evolutionaliry related with our genes, thus, jellyfish already gain molecular system for lens conformation before establishing nervous system. Now, we still continue more fine analysis of the data.

为了了解各种眼睛的形成过程和起源，我利用下一代序列技术进行了比较进化研究。为此，我取了两种不同类型的水母，有眼睛和没有眼睛，也取了不同类型的水晶体眼睛的鞭毛藻。下一代测序技术RNA-seq采集了该物种的基因表达谱。鞭毛藻的视觉色素与细菌色素具有相似性，提示其眼状结构的起源与细菌起源有关。另一方面，水母的研究结果表明，与晶状体发育相关的分子进化与我们的基因有关，因此，水母在建立神经系统之前就已经获得了晶状体构象的分子系统。现在，我们仍在继续对数据进行更精细的分析。