Physio-Anthoropological study on non-visual effects of blue-pulsed light

蓝色脉冲光非视觉效应的生理人类学研究

• 批准号: 23370104
• 负责人: KATSUURA Tetsuo
• 金额: $ 12.06万
• 依托单位: Chiba University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23370104/
• 关键词: 生理人類学; 青色パルス光; 非視覚的作用; 発光ダイオード; 縮瞳; 網膜電図; 劣加法性; 発光ダイオード(LED); 単波長光

The purpose of this study was to clarify the non-visual effects of blue-pulsed light. We observed that the nonvisual effect pupillary constriction (miosis) occurred even during blue-pulsed light irradiation of very short pulse widths (0.5-2 us). When the product of irradiance intensity and the pulse width were equal, the condition of high irradiance and short pulse width was shown to produce marked miosis. The miosis during blue light exposure was stronger than that during simultaneous exposure to blue and green light, and the alpha attenuation coefficient of the EEG for blue light exposure was also greater than that during simultaneous exposure to blue and green light, despite the double irradiance intensity of the combination. We confirmed the subadditive response to pulsed light. Even when the photon density was same, the electroretinogram photopic negative response (PhNR) during the blue-pulsed light exposure was greater than those during the exposure to lights of other colors.

这项研究的目的是阐明蓝色脉冲光的非视觉效应。我们观察到，即使在非常短的脉冲宽度(0.5-2us)的蓝色脉冲光照射下，也会发生非视觉效应的瞳孔收缩(缩影)。当辐照度与脉宽的乘积相等时，高辐照度和短脉宽的情况下会产生明显的缩影。蓝光照射时的缩影比蓝绿光同时照射时强，蓝光照射时脑电的α衰减系数也大于蓝绿光同时照射时的α衰减系数，尽管蓝光和绿光组合的照射强度是蓝绿光同时照射的两倍。我们证实了脉冲光的亚加性响应。即使在光子密度相同的情况下，蓝光脉冲照射时视网膜电信号的明视负反应(PhNR)也比其他颜色的光暴露时的大。

项目成果

皮膚電極による網膜電図測定について -ERG成分における青色パルス光のipRGCへの影響-

关于使用皮肤电极进行视网膜电图测量 - 蓝色脉冲光对 ERG 成分中 ipRGC 的影响 -

• 发表时间: 2013
• 作者: 前田享史;竹中基裕;飯田有俊;倉前正志;横山真太郎;野崎翔大
• 通讯作者: 野崎翔大

青色パルス光の光強度と照射時間の違いが覚醒水準と瞳孔径に及ぼす影響

蓝色脉冲光光强和照射时间差异对觉醒水平和瞳孔直径的影响

• 发表时间: 2012
• 作者: Kyoto;Japan;隅山健太;内田友里亜
• 通讯作者: 内田友里亜

Sub-additive response to pulsed light on arousal level and miosis during daytime

白天对脉冲光的唤醒水平和瞳孔缩小的亚加性反应

• 发表时间: 2013
• 作者: Soomin Lee;Shougo Ishibashi;Yoshihiro Shimomura;Tetsuo Katsuura
• 通讯作者: Tetsuo Katsuura

青色および緑色LEDのパルス光照射における劣加法性

蓝色和绿色 LED 脉冲光照射的次加性

• 发表时间: 2012
• 作者: 飯田有俊;前田享史;竹中基裕;横山真太郎;倉前正志;石橋彰吾
• 通讯作者: 石橋彰吾

青色光のパルス幅による瞳孔径の変化

蓝光脉冲宽度导致的瞳孔直径变化

• 发表时间: 2011
• 作者: Isobe;Kotoha;野崎翔大
• 通讯作者: 野崎翔大