权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Physio-Anthropological Study on Polymorphism of Physiological Responses to Artificial Environments

人工环境生理反应多态性的生理人类学研究

基本信息

批准号：
15107005
负责人：
KATSUURA Tetsuo
金额：
$ 67.39万
依托单位：
Chiba University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (S)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2007
项目状态：
已结题

项目摘要

The purpose of this study was to examine the physiological polymorphism of human responses to various factors of the environment, such as lighting, sound, stress, etc. First, we examined the effects of light on cognition taste thresholds, saliva secretion, and electrogastrogram in relation to subjects' personality types (Type A and B) in 40 men, and found differences in these physiological responses to light in the Type A and Type B subjects.Second, we investigated whether the response to a sound differs depending on behavior patterns (morning and evening types), and showed that the P300 responses to the sound were different in the morning- and the evening-type subjects. We also studied the effect of a synthesized voice on autonomic and central nervous systems, and psychological responses in relation to the gender of the audience, and described the interaction.Next, we investigated the physiological responses to low-relative-humidity air, and found that the saccharin clearance time of the elderly subjects increased more than that of younger subjects, which indicated that the elderly are more sensitive to this condition than younger subjects. We studied the effects of the tolerance of hypoxia on thermoregulatory responses in 54 subjects, and found the higher hypoxic tolerance group showed better body core temperature regulation. We also measured the inter-threshold zones during heat and cold exposure, and revealed the significant effects of non-thermal factors, such as quality of sleep and sensitivity to the heat and cold, on the inter-threshold zones.Finally, we investigated the circulatory responses to mental stress in 59 subjects, and showed that the response types could be roughly classified into two groups; one characterized by increased cardiac output and the other characterized by increased total peripheral resistance. We also revealed the possibility of sub-types from the perspective of the stability and amplitude of these responses.

本研究的目的是检查人类对各种环境因素（如光照、声音、压力等）反应的生理多态性。首先，我们检查了 40 名男性受试者的人格类型（A 型和 B 型）中光对认知味觉阈值、唾液分泌和胃电图的影响，发现 A 型和 B 型受试者对光的生理反应存在差异。研究人员对声音的反应是否因行为模式（早晨型和晚上型）的不同而不同，结果表明，早晨型和晚上型受试者的 P300 对声音的反应不同。我们还研究了合成声音对自主神经和中枢神经系统的影响，以及与观众性别相关的心理反应，并描述了交互作用。接下来，我们研究了对低相对湿度空气的生理反应，发现老年受试者的糖精清除时间比年轻受试者增加更多，这表明老年人比年轻受试者对这种情况更敏感。我们研究了 54 名受试者的耐缺氧能力对体温调节反应的影响，发现耐缺氧能力较高的组表现出更好的体温调节能力。我们还测量了热暴露和冷暴露期间的阈间区，并揭示了非热因素（例如睡眠质量和对热和冷的敏感性）对阈间区的显着影响。最后，我们调查了 59 名受试者对精神压力的循环反应，结果表明反应类型可大致分为两类：一种以心输出量增加为特征，另一种以总外周阻力增加为特征。我们还从这些响应的稳定性和幅度的角度揭示了子类型的可能性。