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Physio-Anthropological Study on Polymorphism of Physiological Responses to Artificial Environments

人工环境生理反应多态性的生理人类学研究

基本信息

批准号：
15107005
负责人：
KATSUURA Tetsuo
金额：
$ 67.39万
依托单位：
Chiba University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (S)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2007
项目状态：
已结题

项目摘要

The purpose of this study was to examine the physiological polymorphism of human responses to various factors of the environment, such as lighting, sound, stress, etc. First, we examined the effects of light on cognition taste thresholds, saliva secretion, and electrogastrogram in relation to subjects' personality types (Type A and B) in 40 men, and found differences in these physiological responses to light in the Type A and Type B subjects.Second, we investigated whether the response to a sound differs depending on behavior patterns (morning and evening types), and showed that the P300 responses to the sound were different in the morning- and the evening-type subjects. We also studied the effect of a synthesized voice on autonomic and central nervous systems, and psychological responses in relation to the gender of the audience, and described the interaction.Next, we investigated the physiological responses to low-relative-humidity air, and found that the saccharin clearance time of the elderly subjects increased more than that of younger subjects, which indicated that the elderly are more sensitive to this condition than younger subjects. We studied the effects of the tolerance of hypoxia on thermoregulatory responses in 54 subjects, and found the higher hypoxic tolerance group showed better body core temperature regulation. We also measured the inter-threshold zones during heat and cold exposure, and revealed the significant effects of non-thermal factors, such as quality of sleep and sensitivity to the heat and cold, on the inter-threshold zones.Finally, we investigated the circulatory responses to mental stress in 59 subjects, and showed that the response types could be roughly classified into two groups; one characterized by increased cardiac output and the other characterized by increased total peripheral resistance. We also revealed the possibility of sub-types from the perspective of the stability and amplitude of these responses.

本研究的目的是探讨人类对各种环境因素的反应的生理多态性，如照明，声音，压力等。首先，我们研究了光对认知味觉阈值，唾液分泌和胃电图的影响与受试者的人格类型（A型和B型），并发现A型和B型受试者对光的这些生理反应存在差异。我们研究了对声音的反应是否因行为模式而异，结果表明，早晨型和晚上型被试对声音的P300反应存在差异。我们还研究了合成声音对自主神经和中枢神经系统的影响，以及与听众性别有关的心理反应，并描述了相互作用。接下来，我们研究了低相对湿度空气的生理反应，发现老年人的糖精清除时间比年轻人增加，这表明老年人对这种情况比年轻人更敏感。本文研究了54名受试者的低氧耐受性对体温调节的影响，发现低氧耐受性高的受试者体温调节功能较好。同时，我们还测量了热暴露和冷暴露时的阈间区，揭示了睡眠质量和冷热敏感性等非热因素对阈间区的显著影响。一种以增加的心输出量为特征，另一种以增加的总外周阻力为特征。我们还从这些反应的稳定性和幅度的角度揭示了亚型的可能性。