Functional pathways in primate retina

灵长类动物视网膜的功能通路

• 批准号: LX0454409
• 负责人: Prof Paul Martin
• 金额: $ 0.37万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage - International
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LX0454409
• 关键词: Functional; pathways; primate; retina

When light enters the eye, specialised nerve cells called photoreceptors transform the light signal into nerve signals. These signals are processed in the retina by two groups of neurones, bipolar and ganglion cells before being sent to higher brain centres. Bipolar and ganglion cells can be subdivided into several types. We will measure which types communicate with each other and which proteins (neurotransmitter receptors) are involved at the site of communication between these nerve cells. This study will improve our knowledge of the basis of functional subspecialisation at the earliest stages of the visual process.

当光线进入眼睛时，被称为光感受器的专门神经细胞将光信号转化为神经信号。这些信号在视网膜中由两组神经元（双极细胞和神经节细胞）处理，然后被发送到更高的大脑中心。双极细胞和神经节细胞可以细分为几种类型。我们将测量哪种类型的神经元之间相互交流，以及哪些蛋白质（神经递质受体）参与了这些神经元之间的交流。这项研究将提高我们的知识的基础上的功能亚专业化在视觉过程的最早阶段。