Elucidation of molecular mechanisms underlying inhibitory effects of glutathione on cadmium translocation and accumulation in plants

镉是一种有害的重金属元素，对食品安全的关注日益增加，建立一种降低作物中镉含量的新技术已成为迫切需要解决的问题。在我们的研究中，我们发现谷胱甘肽（GSH）特异性地施用于植物根部，抑制了Cd从根部向茎部的转运和Cd在茎部的积累。利用这一现象，并进行一些实际应用的研究，有望建立一种新的栽培技术。在本研究中，我们试图阐明这一现象的分子机制。我们发现这一现象的原因之一是谷胱甘肽应用于根部，激活了Cd从根部流出。

Growing interests in food safety make it an urgent issue to establish a new technique to reduce cadmium (Cd), which is one of harmful heavy metal elements, in crop plants. In our research, we found that glutathione (GSH), which was applied to plant roots site-specifically, inhibited Cd translocation from roots to shoots and Cd accumulation in their shoots. It is expected to establish a novel cultivation technique by applying this phenomenon and carrying out some research for practical use. In this research, we tried to elucidate the molecular mechanism of this phenomenon. We found one of the causes for this phenomenon was that glutathione, applied to roots, activated Cd efflux from their roots.