Development of an artificial feedback system with abdominal electrical stimulation for treatment of orthostatic hypotension

开发用于治疗直立性低血压的腹部电刺激人工反馈系统

• 批准号: 23500560
• 负责人: YAMASAKI FUMIYASU
• 金额: $ 3.33万
• 依托单位: Kochi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23500560/
• 关键词: 先端機能デバイス; 医療・福祉; 医療工学; 起立性低血圧; 低侵襲治療システム

We developed prototype of a noninvasive artificial feedback system with abdominal electrical stimulation, and evaluated an efficacy for treatment of orthostatic hypotension. The frequency responses were identifiable and the step response function showed arterial pressure quickly responded to the stimulation and reached 90% of the steady-state response in 20 seconds. The steady state gain was 0.2+-0.07 mmHg/Hz. On the basis of these results, Kp was set at 1.0, and Ki was set at 0.01, so that the servo system could quickly and effectively attenuate the effect of the external disturbance. The system could prolonged a tilting time in patients with autonomic orthostatic hypotension from 2.3 minutes to 3.2 minutes. Moreover, it could extend to 4.4 minutes by pressing lower limbs with air pants of 40mmHg.

我们研制了一个无创性人工反馈系统的原型，并评估了治疗直立性低血压的疗效。频率响应是可识别的，阶跃响应函数显示动脉压对刺激快速响应，并在20秒内达到稳态响应的90%。稳态增益为0.2 ± 0.07 mmHg/Hz。基于这些结果，Kp被设定为1.0，Ki被设定为0.01，使得伺服系统可以快速有效地衰减外部干扰的影响。该系统可使植物性直立性低血压患者的倾斜时间从2.3分钟延长到3.2分钟。用40 mmHg的空气裤压迫下肢可延长至4.4min。

项目成果

新型人工膵臓STG-55TM が看護師業務に及ぼす影響についての検討

新型人工胰腺STG-55TM对护理工作影响的研究

• 发表时间: 2013
• 作者: 壬生季代;北川博之;宗景匡哉;矢田部智昭;山崎文靖;花崎和弘
• 通讯作者: 花崎和弘