Study on factors for accumulation of intra- and extra-myocellular lipids

本研究的目的是调查骨骼肌脂质含量与年龄、性别、身体健康或锻炼之间的关系。采用质子磁共振波谱法（1H-MRS）测定股四头肌的细胞内脂质（IMCL）和细胞外脂质（EMCL）。结果表明，IMCL与女性的年龄和vo2峰值相关，但与男性无关。EMCL与年龄、Vo2peak在女性中呈正相关，在男性中呈负相关。我们没有观察到急性运动或运动训练对骨骼肌脂质含量的任何显著影响。

The purpose of the present study was to investigate the relationships between skeletal muscle lipid contents and age, sex, or physical fitness or exercise. We determined intramyocellular lipids (IMCL) and extramyocellular lipids (EMCL) by proton magnetic resonance spectroscopy (1H-MRS) of quadriceps muscle. The results suggest that IMCL correlated with age and Vo2peak in women, but did not in men. The EMCL and age or Vo2peak showed positive relationship in women, but negative relationship in men. We did not observe any significant effects of acute exercise or exercise training on skeletal muscle lipid contents.