Study on the exact mechanism for the polychlorinated biphenyl-induced decrease in the serum thyroxine level
Study on the exact mechanism for the polychlorinated biphenyl-induced decrease in the serum thyroxine level
批准号:
23510083
负责人:
KATO Yoshihisa
金额:
$3.49万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-28 至 2015-03-31
中文摘要
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2,2',4,5,5'-Pentachlorobiphenyl-mediated inhibition of a serum T4-transthyretin complex formation is one of causes for the PCB-induced changes in the serum and hepatic T4 levels in mice.
2,2,4,5,5-五氯联苯介导的血清 T4-运甲状腺素蛋白复合物形成抑制是 PCB 诱导小鼠血清和肝脏 T4 水平变化的原因之一。
DOI:
--
发表时间:
2012
期刊:
Organohalogen Compds
影响因子:
--
作者:
[Sakamoto M, Chan HM, Domingo JL, Kawakami S, Murata K., Yoshihisa Kato]
通讯作者:
Yoshihisa Kato
Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy
通过脑苯二氮卓受体占用评价咪达唑仑与熊去氧胆酸、酮康唑和地塞米松的药代动力学相互作用
DOI:
--
发表时间:
2011
期刊:
J Pharm. Pharmacol.
影响因子:
--
作者:
[Murata K, Yoshida M, Sakamoto M, Iwai-Shimada M, Yaginuma-Sakurai K, Tatsuta N, Iwata T, Karita K, Nakai K., Shingen Misaka]
通讯作者:
Shingen Misaka
DOI:
10.1248/bpb.b13-00775
发表时间:
2014-03-01
期刊:
BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子:
2
作者:
[Kato, Yoshihisa, Haraguchi, Koichi, Degawa, Masakuni]
通讯作者:
Degawa, Masakuni
2,2',3,4',5,5'-六塩素化ビフェニル(CB146)のin vivo代謝の動物種差.
2,2,3,4,5,5-六氯联苯(CB146)体内代谢的动物物种差异。
DOI:
--
发表时间:
2013
期刊:
福岡医学雑誌
影响因子:
--
作者:
[太田千穂, 加藤善久, 原口浩一, 遠藤哲也, 古賀信幸, Xiong Y, 太田千穂]
通讯作者:
太田千穂
In vitro metabolism of 3,5,6,7,8,3’,4’-heptamethoxyflavone by rat liver microsomes
大鼠肝微粒体对3,5,6,7,8,3,4-七甲氧基黄酮的体外代谢
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Nobuyuki Koga, Mikiko Matsuoka, Chiho Ohta, Yoshihisa Kato, Koichi Haraguchi, Osamu Kimura and Tetsuya Endo]
通讯作者:
Osamu Kimura and Tetsuya Endo
共 39 条
Elucidation of the mechanism for the chemical substances such as polychlorinated biphenyls induced decrease in the serum thyroxine level
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批准号:18K11660
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2018
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负责人:KATO Yoshihisa
-
依托单位:
Chemical oceanographic section study of dissolved barium in the western Indian Ocean
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批准号:22510018
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.66万
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财政年份:2010
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负责人:KATO Yoshihisa
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依托单位:
Latitudinal section mapping of pore water constituents in the central and eastern equatorial Pacific
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批准号:19510014
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:KATO Yoshihisa
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依托单位:
A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls
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批准号:18510061
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.71万
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财政年份:2006
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负责人:KATO Yoshihisa
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依托单位:
Development of Ba-Si/N diagram in the ocean
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批准号:15510010
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.6万
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财政年份:2003
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负责人:KATO Yoshihisa
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依托单位:
Species differences among mice, hamsters, rats and guinea pigs in PCB-induced alteration of serum thyroid hormone level
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批准号:15510058
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2003
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负责人:KATO Yoshihisa
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依托单位:
Methylsulfonyl metabolites of polychlorinated biphenyl and polybrominated biphenyl as disrupters of endocrine action
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批准号:12680549
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:2000
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负责人:KATO Yoshihisa
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依托单位:
Comparative paleoceanographical study using piston cores from Okhotsk Basin and Suiko Sea Mount
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批准号:11640491
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:1999
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负责人:KATO Yoshihisa
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依托单位:
The role of 3-methylsulfony (3-MeSOィイD22ィエD2) metabolites in the induction of hepatic microsomal drug-metabolizing enzymes by PCB congeners, and the toxicological effects of the MeSOィイD22ィエD2 metabolites of PCB congeners
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批准号:09680531
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:1997
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负责人:KATO Yoshihisa
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依托单位:
北西太平洋における海洋古環境の観測タワーとしての孤立海山の利用とその検証
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批准号:09640586
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1997
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负责人:KATO Yoshihisa
-
依托单位: