Self and non self recognition in a marine sponge, Halichondria okadai

海洋海绵 Halichondria okadai 的自我和非自我识别

• 批准号: 23570106
• 负责人: SAITO Yasunori
• 金额: $ 3.24万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23570106/
• 关键词: カイメン類; 自己・非自己認識; 遺伝的多様性; 移植免疫; sponge; Halichondria okadai; allorecognition; xenorecognition; assay system; 移植免疫能; キメラ; chimera; reaggregation

The function of self and nonself recognition in a marine sponge Halichondria okadai was studied. An adult individual showed rejection against the individual of Halichondria japonica, when they came in contact with each other. The individual of H. okadai also recognized most of allogeneic ones as nonself. Furthermore, just after the metamorphosis of planktonic larvae from a mother individual into young individuals, they showed the ability of allorecognition among their siblings, that is, two young individuals fused with each other or rejected at their contact area. In H. okadai, the manner of xenorejection against individuals of H. japonica was different from that of allorejection, and the manner of allorejection of adult individuals was also different from the manner shown by young individuals. Then, to discuss the genetic control of allorecognition in H. okadai, we have examined the frequency of fusion and rejection among natural populations and among cultured siblings.

研究了冈田软海绵（Halichondriaokadai）的自我和非自我识别功能。一个成年个体对日本软海绵个体表现出排斥反应，当它们相互接触时。H.冈代也将大多数同种异体的生物识别为非我。此外，在从母体到幼体的变态过程中，它们表现出同胞之间的异源识别能力，即两个幼体在接触区域相互融合或排斥。In H. okadai，H.结果表明，日本血吸虫的同种异体排斥反应与同种异体排斥反应不同，成年个体的同种异体排斥反应与青年个体的同种异体排斥反应也不同。探讨了H.冈代，我们已经检查了自然种群和培养的同胞之间的融合和排斥的频率。

项目成果

Self and nonself recognition in a marine sponge, Halichondria japonica (Demospongiae)

海洋海绵 Halichondria japonica (Demospongiae) 的自我和非自我识别

• 发表时间: 2013
• 期刊: Zool. Sci.
• 作者: Saito;Y.
• 通讯作者: Y.

クロイソカイメンの自己・非自己認識

黑海海绵的自我/非自我识别

• 发表时间: 2012
• 作者: Kambe Y;Nakata K;Yasuda SP;Suzuki H;Uchida K and Ushimaru A;齊藤康典
• 通讯作者: 齊藤康典

LABORATORY OF DEVELOPMENTAL BIOLOGY

发育生物学实验室