Isolation and characterization of ubiquitin-like protein MNSF-conjugating enzymes
Isolation and characterization of ubiquitin-like protein MNSF-conjugating enzymes
批准号:
23570138
负责人:
NAKAMURA Morihiko
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
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英文摘要
In this study, we identified and characterized an enzyme which conjugates MNSF to target protein(s). This enzyme is a novel protein similar to ubiquitin conjugating enzyme E3. In addition, we also identified a heat shock protein which stabilizes aggregative MNSF. Thus, the mechanism of MNSF conjugation was partly shown.
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Ubiquitin-like protein MNSFβcovalently binds to Bcl-G and enhances lipopolysaccharide (LPS)/interferonγ(IFNγ)-induced apoptosis in macrophages
泛素样蛋白 MNSFβ 与 Bcl-G 共价结合并增强脂多糖 (LPS)/干扰素 γ (IFNγ) 诱导的巨噬细胞凋亡
DOI:
--
发表时间:
2013
期刊:
FEBS J.
影响因子:
--
作者:
[Wtanabe J, Nakagawa M, Nakamura M.]
通讯作者:
Nakamura M.
Preliminary study on using accelerometers to measure involuntary movement for the assessment of neurological motor impairments
使用加速度计测量不自主运动评估神经运动障碍的初步研究
DOI:
--
发表时间:
2013
期刊:
Advanced Applied Informatics
影响因子:
--
作者:
[Iwasaki Y, Hirotomi T, Oguro H, Nakamura M.]
通讯作者:
Nakamura M.
DOI:
10.1007/s11010-011-1202-x
发表时间:
2012-05-01
期刊:
MOLECULAR AND CELLULAR BIOCHEMISTRY
影响因子:
4.3
作者:
[Nakamura, Morihiko, Watanabe, Jun, Watanabe, Natsuko]
通讯作者:
Watanabe, Natsuko
Ubiquitin-like protein MNSFβenhances LPS/IFNγ- induced apoptosis in macrophages
泛素样蛋白 MNSFβ 增强 LPS/IFNγ 诱导的巨噬细胞凋亡
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Watanabe J, Watanabe N, Nakamura M.]
通讯作者:
Nakamura M.
Chronic administration of cardanol (ginkgol) extracted from ginkgo biloba leaves and cashew nutshell liquid improves working memory-related learning in rats.
长期服用从银杏叶和腰果壳液中提取的腰果酚(银杏酚)可改善大鼠与工作记忆相关的学习。
DOI:
10.1248/bpb.35.127
发表时间:
2012
期刊:
Biological & pharmaceutical bulletin
影响因子:
2
作者:
[S. Tobinaga, M. Hashimoto, I. Utsunomiya, K. Taguchi, Morihiko Nakamura, T. Tsunematsu]
通讯作者:
T. Tsunematsu
共 19 条
Ubiquitin-like MNSFβ regulates apoptosis
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批准号:19570131
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
-
财政年份:2007
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负责人:NAKAMURA Morihiko
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依托单位:
Characterization of ubiquitin-like polypeptide acceptor protein, a novel pro-apoptotic member of the Bcl-2 family
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批准号:15570118
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2003
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负责人:NAKAMURA Morihiko
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依托单位:
Novel mechanism of action of monoclonal nonspecific suppressor factor (MNSF)
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批准号:13680715
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2001
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负责人:NAKAMURA Morihiko
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依托单位:
STUDY ON THE MODE OF ACTION OF MONOCLONAL NONSPECIFIC SUPPRESSOR FACTOR (MNSF)
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批准号:08670367
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.22万
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财政年份:1996
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负责人:NAKAMURA Morihiko
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依托单位:
海外基金