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Isolation and characterization of ubiquitin-like protein MNSF-conjugating enzymes

Isolation and characterization of ubiquitin-like protein MNSF-conjugating enzymes
泛素样蛋白 MNSF 结合酶的分离和表征
批准号:
23570138
负责人:
NAKAMURA Morihiko
金额:
$3.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
In this study, we identified and characterized an enzyme which conjugates MNSF to target protein(s). This enzyme is a novel protein similar to ubiquitin conjugating enzyme E3. In addition, we also identified a heat shock protein which stabilizes aggregative MNSF. Thus, the mechanism of MNSF conjugation was partly shown.
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会议论文
Ubiquitin-like protein MNSFβcovalently binds to Bcl-G and enhances lipopolysaccharide (LPS)/interferonγ(IFNγ)-induced apoptosis in macrophages
泛素样蛋白 MNSFβ 与 Bcl-G 共价结合并增强脂多糖 (LPS)/干扰素 γ (IFNγ) 诱导的巨噬细胞凋亡
DOI: --
发表时间: 2013
期刊: FEBS J.
影响因子: --
作者: [Wtanabe J, Nakagawa M, Nakamura M.]
通讯作者: Nakamura M.
DOI: --
发表时间: 2013
期刊: Advanced Applied Informatics
影响因子: --
作者: [Iwasaki Y, Hirotomi T, Oguro H, Nakamura M.]
通讯作者: Nakamura M.
DOI: 10.1007/s11010-011-1202-x
发表时间: 2012-05-01
期刊: MOLECULAR AND CELLULAR BIOCHEMISTRY
影响因子: 4.3
作者: [Nakamura, Morihiko, Watanabe, Jun, Watanabe, Natsuko]
通讯作者: Watanabe, Natsuko
Ubiquitin-like protein MNSFβenhances LPS/IFNγ- induced apoptosis in macrophages
泛素样蛋白 MNSFβ 增强 LPS/IFNγ 诱导的巨噬细胞凋亡
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Watanabe J, Watanabe N, Nakamura M.]
通讯作者: Nakamura M.
19
    Ubiquitin-like MNSFβ regulates apoptosis
    • 批准号:
      19570131
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2007
    • 负责人:
      NAKAMURA Morihiko
    • 依托单位:
    Characterization of ubiquitin-like polypeptide acceptor protein, a novel pro-apoptotic member of the Bcl-2 family
    Novel mechanism of action of monoclonal nonspecific suppressor factor (MNSF)
    • 批准号:
      13680715
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.11万
    • 财政年份:
      2001
    • 负责人:
      NAKAMURA Morihiko
    • 依托单位:
    STUDY ON THE MODE OF ACTION OF MONOCLONAL NONSPECIFIC SUPPRESSOR FACTOR (MNSF)
    • 批准号:
      08670367
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.22万
    • 财政年份:
      1996
    • 负责人:
      NAKAMURA Morihiko
    • 依托单位:
    海外基金