Basic studies on development of a novel delivery system of materials into fish oocytes

卵黄前体卵黄蛋白原（Vg）与卵巢Vg受体结合后，从母体血液中选择性地掺入卵母细胞。这项研究表明，从异源物种获得的Vg，以及Vg与自愿脂质耦合，可以通过注射到亲鱼卵和后代。这表明鱼Vg作为生物活性物质的转运体的潜在用途;该系统可以通用于任何鱼类物种。该研究还证实，发现这种系统适用于跨代向卵和后代递送生物活性脂质和/或疏水材料。

A yolk precursor vitellogenin (Vg) is selectively incorporated from the maternal blood into oocyte following its binding to ovarian Vg receptor. This study demonstrated that Vg obtained from heterologous species, as well as Vg coupled with voluntary lipids, can be delivered to fish eggs and offsprings by injecting them into broodstocks. This indicated a potential use of fish Vg as a transporter of bioactive materials; the system can be universal to any fish species. This study also confirmed that such system was found to be applicable for the delivery of bioactive lipids and/or hydrophobic materials to eggs and offsprings across generations.