Establishment of novel and objective ultrasonographic examination and its application to clinical veterinary medicine

新颖客观超声检查方法的建立及其在临床兽医中的应用

• 批准号: 23580436
• 负责人: TAKIGUCHI MITSUYOSHI
• 金额: $ 3.49万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23580436/
• 关键词: 超音波検査; 造影超音波検査; 膵臓; 犬; 膵炎; 超音波造影剤; ソナゾイド; 超音波診断

To establish novel and objective ultrasonographic examination and apply it to clinical veterinary medicine, fundamental parameters of normal canine pancreatic perfusion were determined by using contrast agent Sonazoid. Then, novel diagnostic critetria for acute pancreatitis focused on pancreatic perfusion changes was established based on analysis of contrast-enhanced ultrasonographic examination in experimentally induced acute pancreatitis model in the dog.In addition, left atrial phasic function in healthy dogs by means of 2-D speckle tracking echocardiography with time-left atrial area curve analysis was evaluated. The repeatability and reproducibility of obtained measurements were adequate. This results indicates that studies are needed to determine clinical applicability in canine patients.

为建立一种新颖、客观的超声检查方法，并将其应用于兽医临床，本研究采用Sonazoid声学造影剂，对正常犬胰腺血流灌注的基本参数进行了测定。在此基础上，通过对犬急性胰腺炎模型的超声造影分析，建立了以胰腺血流灌注变化为核心的急性胰腺炎诊断新标准，并应用二维斑点追踪超声心动图结合时间-左房面积曲线分析评价了健康犬左房相位功能。所获得的测量结果的重复性和再现性是足够的。这一结果表明，需要研究来确定犬患者的临床适用性。

项目成果

Qualitative and quantitative contrast enhanced ultrasonographic assessment of cerulein-induced pancreatitis in dogs

犬雨蛙素诱发的胰腺炎的定性和定量对比增强超声评估

• 发表时间: 2013
• 作者: Lim SY;Nakamura K;Morishita K;Sasaki N;Murakami M;Osuga T;Ohta H;Yamasaki M;Takiguchi M.
• 通讯作者: Takiguchi M.

超音波診断装置、超音波診断方法

超声波诊断装置、超声波诊断方法

• 发表时间: 2012

Repeatability and reproducibility of measurements obtained via two-dimensional speckle tracking echocardiography of the left atrium and time-left atrial area curve analysis in healthy dogs.

通过健康犬左心房二维斑点追踪超声心动图和时间-左心房面积曲线分析获得的测量结果的重复性和再现性。

• 发表时间: 2013
• 期刊: Am J Vet Res
• 影响因子: 1
• 作者: Osuga T;Nakamura K;Lim SY;Tamura Y;Rajapakshage BKW;Murakami M;Sasaki N;Morishita K;Ohta H;Yamasaki M;Takiguchi M
• 通讯作者: Takiguchi M

Qualitative and quantitative contrast enhanced ultrasonographic assessment of cerulein- induced pancreatitis in dogs

狗雨蛙素诱发的胰腺炎的定性和定量对比增强超声评估

• 发表时间: 2013
• 作者: Lim SY;Nakamura K;Morishita K;Ohta H;Yamasaki M;Takiguchi M.
• 通讯作者: Takiguchi M.

ソナゾイド造影超音波検査と機械学習を組み合わせた脾臓腫瘤の自動良悪性鑑別の試み

尝试结合 Sonazoid 对比超声检查和机器学习自动区分脾肿块的良恶性

• 发表时间: 2012
• 作者: Murai;A.;Asa;SA.;Kodama;A.;Sakai;H.;Hirata;A. and Yanai ;T.;加藤大智;中村健介,高木一也,近藤敏志,滝口満喜
• 通讯作者: 中村健介,高木一也,近藤敏志,滝口満喜