Novel evaluation method using 3D OCT for safety of drug eluting stent

利用3D OCT评估药物洗脱支架安全性的新方法

• 批准号: 23591045
• 负责人: OKAMURA Takayuki
• 金额: $ 3.49万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23591045/
• 关键词: 虚血性心疾患; 冠動脈ステント; 光干渉断層法; 動脈硬化; 画像診断

We have developed a novel method to evaluate the tissue coverage using 3-dimensional optical coherence tomography. It had a good correlation to the standard quantitative analysis. The tissue coverage after biolimus- and evarolimus-eluting stent were evaluated by this method and good tissue coverage was revealed at 1-year follow-up. Furthermore, it has been reported that a lipid rich plaque with thin-fibrous cap related to occurrence of acute coronary syndrome and stent-related events. We have developed novel software which demonstrates such vulnerable plaque on 3-dimensional vessel model to facilitate understanding its location.

我们已经开发了一种新的方法来评估使用三维光学相干断层扫描的组织覆盖。与标准定量分析结果具有良好的相关性。通过该方法评价了biolimus和evarolimus洗脱支架后的组织覆盖，在1年随访时显示组织覆盖良好。此外，据报道，富含脂质的斑块和薄纤维帽与急性冠状动脉综合征和支架相关事件的发生有关。我们开发了一种新的软件，可以在三维血管模型上显示这种易损斑块，以便于了解其位置。

项目成果

Three-dimensional assessment of Everolimus vs Biolimus eluting stent based on serial optical coherence tomography

基于串行光学相干断层扫描的依维莫司与 Biolimus 洗脱支架的三维评估

• 发表时间: 2014
• 作者: Maeda T;Okamura T;Yamada J;Nao T;Oda T;Mochizuki M;Tateishi H;Shiraishi K;Nakashima T;Nakamura T;Nishimura S;Yano M.
• 通讯作者: Yano M.

Three-dimensional optical coherence tomography assessment for strut coverage of sirolimus vs everolimus eluting stent at follow-up

三维光学相干断层扫描评估西罗莫司与依维莫司洗脱支架的支架覆盖率

• 发表时间: 2013
• 作者: Maeda T;Okamura T;Yoshimura M;Oda T;Shiraishi K;Nakashima T;Nakamura T;Miura T;Yano M.
• 通讯作者: Yano M.

OCTの３次元イメージングをPCIに活用する

利用 OCT 3D 成像进行 PCI

• 发表时间: 2012
• 作者: SUZUKI Tomoyuki;MORISHIMA Mikio;KATO Sara;TAKEMOTO Yoshio;TAKANARI Hiroki;UEDA Norihiro;TSUJI Yukiomi;HONJO Haruo;KAMIYA Kaichiro;岡村誉之
• 通讯作者: 岡村誉之

Three-Dimensional Optical Coherence Tomography Assessment of Strut Coverage after Everolimus-Eluting Stent Implantation

依维莫司洗脱支架植入后支柱覆盖度的三维光学相干断层扫描评估

• 发表时间: 2012
• 作者: T Maeda;T Okamura;J Yamada;T Nao;M Yoshimura;T Suetomi;A Hino; T Oda;T Nakashima;K Shiraishi;T Nakashima;T Nakamura;S Nishimura;T Miura;M Matsuzaki
• 通讯作者: M Matsuzaki

Sequel of Jailed Side Branch

监狱支线续集

• DOI: 10.1253/circj.cj-13-0709
• 发表时间: 2014
• 期刊: Circulation Journal
• 影响因子: 3.3
• 作者: Hiroki Tateishi;Takayuki Okamura;Jutaro Yamada;Tomoko Nao;Takao Maeda;Takamasa Oda;Takeshi Nakamura;Toshiro Miura;Masunori Matsuzaki;Masafumi Yano
• 通讯作者: Masafumi Yano