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Evaluation of oxidative stress in children with non-alcoholic steatohepatitis

Evaluation of oxidative stress in children with non-alcoholic steatohepatitis
非酒精性脂肪性肝炎患儿氧化应激的评价
批准号:
23591589
负责人:
TAMAI HIROSHI
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

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中文摘要
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英文摘要
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in developed countries, and its incidence is increasing in adults and children. As an antioxidant, vitamin E is effective in treatment of NAFLD, although the mechanism is still unclear. Methionine-choline deficient (MCD) rats used as an experimental model of NAFLD were fed a vitamin E-enriched diet. In the MCD rats, vitamin E treatment altered the hepatic alpha-tocopherol-related protein expression, which may affect the alpha-tocopherol status in the liver and reduce lipid peroxidation.
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DOI: 10.3177/jnsv.60.78
发表时间: 2014-04-01
期刊: JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
影响因子: 1.6
作者: [Miyazaki, Hiroshi, Takitani, Kimitaka, Tamai, Hiroshi]
通讯作者: Tamai, Hiroshi
DOI: 10.3177/jnsv.59.64
发表时间: 2013-02-01
期刊: JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
影响因子: 1.6
作者: [Miyazaki, Hiroshi, Takitani, Kimitaka, Tamai, Hiroshi]
通讯作者: Tamai, Hiroshi
ビタミンE研究の進歩
维生素E研究进展
DOI: --
发表时间: 2013
期刊:
影响因子: --
作者: [渡邉誠, 深澤隆治, 勝部康弘, 小川俊一, 他, 徳山研一, 玉井浩]
通讯作者: 玉井浩
Case treated with triple therapy of lamivudine, interferon-β and prednisolone for acute exacerbation of chronic hepatitis B during pregnancy.
妊娠期慢性乙型肝炎急性加重接受拉米夫定、干扰素-β和泼尼松龙三联疗法治疗的病例。
DOI: 10.1111/j.1872-034x.2012.01077.x
发表时间: 2013-04
期刊: Hepatology research : the official journal of the Japan Society of Hepatology
影响因子: --
作者: [Koh M, Shinohara J, Hongo Y, Okazaki T, Takitani K, Tamai H]
通讯作者: Tamai H
15
    Novel evaluation method of oxidative stress in pediatric patients with non-alcoholic fatty liver disease
    • 批准号:
      15K09703
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2015
    • 负责人:
      TAMAI HIROSHI
    • 依托单位:
    海外基金