The Relationship between Visceral Fat, Adipoctokines and colorectal neoplasma development evaluated by computed tomography (CT) colonography

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• Obesity, visceral fat is associated with increased risks for colorectal neoplasm, cancer (CRC) and adenomatous polyp (polyp). CT colonography(CTC) is adopted as a new examination tool for colorectal cancer screening. Evaluate the relationship among colorectal neoplasm, visceral adiposity and adipocytokines. 123 patients who underwent both colonoscopy and CTC were enrolled in this study. We classified three patient groups: no lesion (NL; n=40), Adenomatous polyp (Polyp; n=41), early colorectal cancer (eCRC; n=21), and advanced CRC (aCRC; n=21) groups. Total adipose area (TAA), TAA index in both polyp and CRC groups were significantly higher than that in the NL. CT colonography could not be an only useful examination to diagnose colorectal neoplasms, but also to evaluated the visceral obesity, risk factor of polyp, at the same time.